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Posted By : Rockon - 7/19/2017 1:46 AM
Someone in a mast cell group told me this last week, and a neurosurgeon I started following on Facebook just posted this. I take the timing of this just now being posted as a sign I am supposed to pass it along today. Tricyclics include amitriptyline (elavil), nortriptyline (pamelor), doxepin, and several other that are at my bottom link.

I will quote one paragraph, about which drugs are a concern for developing dementia.
"Anticholinergic drugs block the action of acetylcholine. This substance transmits messages in the nervous system. In the brain, acetylcholine is involved in learning and memory. In the rest of the body, it stimulates muscle contractions. Anticholinergic drugs include some antihistamines, tricyclic antidepressants, medications to control overactive bladder, and drugs to relieve the symptoms of Parkinson’s disease."
www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667?utm_content=buffer5f5a8&utm_medium=social&utm_source=facebook.com&utm_campaign=odah-buffer[

Tricyclics
/www.drugs.com/drug-class/tricyclic-antidepressants.html

Post Edited (Rockon) : 7/19/2017 2:15:03 AM (GMT-6)


Posted By : Rockon - 7/19/2017 1:50 AM
The same neurosurgeon posted this on the 15th. He said he has refused to use these meds ever since the vioxx and bextra scandals a decade ago. Turns out he is right about there being problems for some people. As many of you know, NSAIDs will activate mast cells in some mast cell disorder patients. I can get away with the occasional 440 mgs Naprosyn for a headache tho. I only tolerate the gelcapsfor, tho. Fillers must get to me in the hard capsules.Anyways, when nothing is working, a couple days in, I give in and take Naprosyn. I also compromise my principles and use pieces of the flector patch when my jaw gets going.
www.independent.co.uk/news/health/ibuprofen-regularly-one-week-heart-attack-risk-increase-painkillers-common-pills-nsaids-naproxen-a7725736.html

Post Edited (Rockon) : 7/19/2017 2:10:49 AM (GMT-6)


Posted By : Rockon - 7/19/2017 1:54 AM
I also found research about floroquinolone antibiotics being mast cell activators. (I posted the info and a study quote at myPatientMatch if you want to verify the info). I don't know if that is somehow related to the many stories of damage to tendons having occurred. I know the mast cell disorder patient population does not like floroquinolones, reacts poorly to them, and a minority of people in those groups have had tissue damage from them.

Post Edited (Rockon) : 7/19/2017 2:16:32 AM (GMT-6)


Posted By : Sherrine - 7/19/2017 9:08 AM
I have a friend that I've been friends with for 40 years and she has been on Pamelor all of that time. She is now 83 years old and extremely active. It's like she is in her 30's.

And I have been on ibuprofen for 30 years. I did develop an ulcer two times but it healed right away and I'm using the product again. It works like a wonder drug for me and quality of life is an issue for me.

Some people are more sensitive to medications than other people. So many medications have been "linked" to this and that and nothing comes of it. I think it's wise to be informed so I do thank you for sharing this info but if I were taking one of the medications and saw no problems with it, I personally would continue taking it. Pamelor works so well for my friend and she is as sharp mentally as she always has been. And ibuprofen allows me to live a good life with chronic pain.

Sherrine

Forum Moderator/Fibromyalgia

Fibromyalgia, Crohn's Disease, Ostomy, Autoimmune Inner Ear Disease, Diabetes, Osteoporosis, Glaucoma, Scoliosis, Ankylosing Spondylitis
************************
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7

Posted By : Rockon - 7/19/2017 6:51 PM
The neurologist, who's interest is "mitohacking", posted this just now.
It says the articles on Mito damaging meds never get published in mainstream medical journals. Not surprised at this point.
Title
Thanks Big Pharma for the Mitochondrial "collateral damage"

Dr. Gary G. Kohls
Global Research
Fri, 06 May 2016

"During the Q & A, a mitochondrial research scientist in the audience got up and talked about a colleague of his that had written an academic paper that identified 72 commonly-prescribed drugs that were mitochondrial poisons."

/www.sott.net/article/321987-Thanks-Big-Pharma-for-the-Mitochondrial-collateral-damage

XXX XXXXXXXXXXXXXXXXXXXXXXXXXXX
Are dementia numbers growing? Oh yes. Just Google the question.
Alzheimers.org answers
m.alz.org/facts-and-figures.asp

Post Edited (Rockon) : 7/19/2017 6:57:42 PM (GMT-6)


Posted By : Sherrine - 7/20/2017 6:31 AM
We have an Alzheimer's forum on HealingWell. This discussion needs to be there...not in the fibro forum. Thanks!

Sherrine
Forum Moderator/Fibromyalgia

Fibromyalgia, Crohn's Disease, Ostomy, Autoimmune Inner Ear Disease, Diabetes, Osteoporosis, Glaucoma, Scoliosis, Ankylosing Spondylitis
************************
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7

Posted By : Rockon - 7/20/2017 10:08 AM
As someone who was prescribed a mitotoxic medication for my Fibromyalgia for 20 yrs, including for many years after the research showed it was harmful, I disagree. Big Pharma is in control of the information flow, unless we overcome their control online.

Post Edited (Rockon) : 7/20/2017 8:51:13 PM (GMT-6)


Posted By : Sherrine - 7/20/2017 4:38 PM
I do cringe when people refer to pharmaceutical companies as "Big Pharma". It's like they are part of some conspiracy theory. Pharmaceutical companies have created miracle drugs, helped wipe out illnesses like polio, created medications that have extended lives, medications that have cured people, and medications that not only help control illnesses but also give us quality of life.

I'm very thankful for the medications personally. They saved me from possibly contracting polio as a child since the Salk vaccine came out when I was 8 years old. I saw people in iron lungs on the news and plenty of children on crutches and in wheelchairs too. It was rampant.. At 8 years old I was concerned about getting polio. It was a scary time for people and we were so thankful that the pharmaceutical company, along with the scientists who work creating medications and vaccines, developed a way to rid ourselves from this illness.

Antibiotics have helped me throughout the years and the medications I take now help keep diabetes and chronic pain under control, keep my cholesterol and acid reflux under control, keep glaucoma eye pressure in the normal range and even help protect my stomach from ulcers. So I'm thankful for "Big Pharma".

Whenever we put any medication in our bodies there is always a risk. There are side effects to these chemicals since they are making your body react a different way. Some people react differently than others since we are all so different. The medication you have taken for 20 years obviously hasn't caused you Alzheimer's and most likely won't if you haven't shown signs by now. It must have helped you somewhat or you wouldn't have taken it for two decades. I won't take Prilosec because I developed osteoporosis from it but the majority of people don't. If they did, it would be taken off the market. I let members know but I sure don't blame the pharmaceutical companies. This drug helps many and they don't get osteoporosis either!

So, as I said before, I'm glad you gave a heads up. I do not agree there is so me sort of conspiracy going on with the pharmaceutical companies. Members can discuss this with their doctors but, now, do take this to the Alzheimer's forum. I'm sure family members there would be quite interested in your findings.

Sherrine

Forum Moderator/Fibromyalgia

Fibromyalgia, Crohn's Disease, Ostomy, Autoimmune Inner Ear Disease, Diabetes, Osteoporosis, Glaucoma, Scoliosis, Ankylosing Spondylitis
************************
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7

Posted By : Rockon - 7/20/2017 4:46 PM
Google
pharmaceutical companies hide the dangers of medicines
There will be articles from
NIH, NPR, Forbes, NY Times, Scientific American, Harvard University, Washington Post, Drug Safety News, Center for Inquiry, Bloomberg, Drugwatch..and on.
/www.google.com/search?q=pharmaceutical+companies+hide+the+dangers+of+medicines&oq=pharmaceutical+hide+&aqs=chrome.1.69i57j0l2.11288j0j4&client=tablet-android-alco&sourceid=chrome-mobile&ie=UTF-8

Post Edited (Rockon) : 7/20/2017 8:47:24 PM (GMT-6)


Posted By : Rockon - 7/20/2017 4:55 PM
In The New Republic December 2016
Title:Congress Just Quietly Handed Drug Companies a Dangerous Victory

"...under the Act drug firms will increasingly be able to rely on flimsier forms of evidence for approval of their therapies..."
"...The law defines “real world evidence” as “data… derived from sources other than randomized clinical trials,” which is to say uncontrolled observational data."

Later:
“We need to remember,” as former editor-in-chief of the New England Journal of Medicine Marcia Angell wrote in her 2004 pharmaceutical exposé, The Truth about the Drug Companies, “that much of what we think we know about the pharmaceutical industry is mythology spun by the industry’s immense public relations apparatus.”

/newrepublic.com/article/139328/congress-just-quietly-handed-drug-companies-dangerous-victory

Post Edit: folks, you might read the article the doctor wrote,about mitotoxic meds. The title that begins "Big Pharma". It actually is about a conspiracy.

Post Edited (Rockon) : 7/20/2017 8:52:40 PM (GMT-6)


Posted By : Sherrine - 7/20/2017 6:12 PM
Im not sure what they are hiding. Listen to drug ads. They are almost laughable. (I love the one that said if you go blind or deaf, talk to your doctor about it.). They list everything...including death...and so do their brochures. I refused to take several medications after I read the drug brochure.

Sherrine

Forum Moderator/Fibromyalgia

Fibromyalgia, Crohn's Disease, Ostomy, Autoimmune Inner Ear Disease, Diabetes, Osteoporosis, Glaucoma, Scoliosis, Ankylosing Spondylitis
************************
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7

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