The First and Only Prescription Medical Food Product for Managing IBS-D & IBD: EnteraGam®

Manage Your Condition with EnteraGam®

If you suffer from abdominal discomfort, bloating, or chronic diarrhea due to irritable bowel syndrome with diarrhea (IBS-D) or Inflammatory Bowel Disease (IBD), you already know that you often have to change your plans or miss out altogether. These life-disrupting symptoms are the hallmark of IBS-D and IBD. 1-2

EnteraGam® is a prescription medical food product for the dietary management of specific intestinal disorders including IBS-D and IBD, so it could help you avoid having to plan your days around symptoms.3

Simple, Safe, and Unique

EnteraGam® is completely different from other therapies because it uniquely addresses the underlying factors that can cause symptoms of irritable bowel syndrome with diarrhea and inflammatory bowel disease. In a clinical study, people who took EnteraGam® experienced fewer days per week with loose stools and other IBS-D-related symptoms, including abdominal discomfort and bloating. 4

EnteraGam® is safe, well tolerated, and can be taken along with other therapies that your doctor has prescribed. There have been no reported interactions with any other medications and no reports of serious side effects. Plus, you can take EnteraGam® as long as you want, unlike antibiotics that can only be taken for short periods of time. 5

There is no generic prescription product to substitute for it and no over-the-counter (OTC) product like it.

Taking EnteraGam® is Easy!

EnteraGam® is a simple powder that can be easily mixed into water or another liquid that you like, such as a fruit punch-flavored drink. Mix (but do not shake) the entire packet of EnteraGam® with at least 4 ounces of fluid (unless otherwise instructed by your doctor). Then drink all of the contents immediately.

You can also mix EnteraGam® with a favorite soft food, such as pudding or yogurt. Then consume immediately.

Some people notice improvement with EnteraGam® in as little as 2 to 4 weeks. If you do not see results as quickly, talk to your doctor. Everyone is different. Your doctor may decide to change or increase your dose of EnteraGam®. For best results, take EnteraGam® exactly as your doctor has prescribed.

How EnteraGam® Works

Research shows that unhealthy changes in the lining of the intestine may contribute to IBS-D and IBD symptoms 6-7. EnteraGam® has been shown in studies to restore a stable environment in the gut 8. It works differently than products that provide short-term relief of symptoms.

The Hub Provides Prescription Savings Vouchers and More

The Hub is where all of the important EnteraGam® patient support services and information come together in one place for your convenience. There you can learn about and sign up for prescription savings vouchers* and helpful information related to your condition. You can also learn about using EnteraGam® personalized pharmacy services (powered by Foundation Care), where you’ll receive a full-service experience no other retail pharmacy can match. You will be able to get your EnteraGam® prescription delivered right to your door, and it is guaranteed to be available.

Important Safety Information

EnteraGam® contains beef protein; therefore, patients who have an allergy to beef or any component of EnteraGam® should not take this product. The most commonly reported adverse events in clinical studies (incidence of 2-5%) include mild nausea, constipation, stomach cramps, headache, and increased urination. Since there are no studies in patients who are pregnant or nursing, the decision to use EnteraGam® in these populations is at the discretion of the prescriber. EnteraGam®, as a medical food, must be used under physician supervision.

Ask your doctor about EnteraGam®

Download Talking to Your Doctor about EnteraGam®


  1. International Foundation for Functional Gastrointestinal Disorders Web site. IBS with diarrhea. Accessed February 1, 2016.
  2. American Gastroenterological Association Web site. IBS in America. Accessed February 1, 2016.
  3. Petschow BW, Burnett B, Shaw AL, Weaver EM, Klein GL. Serum-derived bovine immunoglobulin/protein isolate: postulated mechanism of action for management of enteropathy. Clin Exp Gastroenterol. 2014;7:181-190.
  4. Wilson D, Evans M, Weaver E, Shaw AL, Klein GL. Evaluation of serum-derived bovine immunoglobulin protein isolate in subjects with diarrhea-predominant irritable bowel syndrome. Clin Med Insights Gastroenterol. 2013;6:49-60.
  5. EnteraGam® [prescribing information]. Ankeny, IA: Entera Health, Inc.; March 2015.
  6. Wilson D et al. Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects with Diarrhea-Predominant Irritable Bowel Syndrome. Clin Med Insights: Gastroenterol 2013: 6:49-60.
  7. Shafran I, Burgunder P, Wei D, Young HE, Klein G, Bruce P. Burnett BP. Management of inflammatory bowel disease patients with oral serum-derived bovine immunoglobulin. Therapeutic Advances in Gastroenterology. 2015; 1–9, DOI: 10.1177/1756283X15593693)
  8. Petschow, BW et al. Serum-Derived Bovine Immunoglobulin/ Protein Isolate: Postulated Mechanism of Action for Management of Enteropathy.  Clinical and Experimental Gastroenterology 2014; 2014:7 181-190.

*The co-pay voucher program is not valid for prescriptions reimbursed under Medicare, Medicaid, Tricare, or any other federal or state program, or where prohibited by law. Even if you don’t have insurance you can still save on EnteraGam®. Call 1-844-368-3721 (1-844-ENTERA1) for more information. Vouchers can also be used at other pharmacies.


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