right now, I have no side effects from the plaquenil. When I first started it, though, I did feel quite nauseated. I made sure to take it after lunch, when I had food in my stomach. When I took it first thing in the morning, the nausea got quite bad for me. Taking it at bedtime might not be a bad idea either (but I never did that). In any case, it went away after about 4 weeks. I guess my system just had to get used to it.
Since the drug helps you so much, I really hope you can work through the stomach issues. Best of luck.
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan