I am currently participating in a clinical trial for the drug that will be marketed as Cimzia. I am taking it primarily for Crohn's Disease but, since it is used for RA also, hoped that it would help with my arthritis (Crohn's related arthritis). I have been on the trial for right at a year. The trial lasted for 6 months and then I had the option to sign on for the long-term phase of the trial, which will last until the drug is available on the market (or rejected by the FDA- whichever happens). I had some concern about taking a drug that had potentially unknown side effects but, since it is so similar to Humira, figured that most of the side effects would be the same as with Humira. The drug helped tremendously until winter came and, since then, my arthritis has been killing me. The only drawback to the trial is that they really limit what other drugs I can start taking (stuff I was already on is okay), as those could interfere with their results. For instance, I can take arthritis medications, as long as they don't also help with Crohn's (which a lot of them can). I am limited on how much steroids I can take, which has limited my ability to get cortisone injections. But, other than that, I have no complaints with doing a clinical trial. I get free medication, get paid for doing it, get to see a doctor and have blood work done every month, etc. As long as it is in the late stages, so they are more aware of the side effects, I would say go for it...I would rather take a drug that could potentially shorten my life span (assuming that early death ended up being some horrible side effect) and have a better, less painful life, than live longer but be miserable the entire time.
...rejoice in our sufferings, because we know that suffering produces perseverence; perseverence, character; and character, hope. Romans 5:3-4