Oh boy, I'm sorry to hear how much you are going through and that the plaquenil is not helping. It took a while for it to really kick in for me (But, if it hasn't kicked in after 7 years...I guess you need something else)
I do want to say some of the meds will lower your white blood count. Methotrexate can do a lot of funky things to you. I had pluerisy (however you spell it) while on it. The docs insisted it was not the drug....but I haven't had it since I stopped taking it. Elavil made me very tired and loopy. I'm currently on a plaquenil/Arava mix and it does help quite a bit, I also have to take Nexium as I feel like my chest is going to explode if I don't as well as a slew of vitamins. I was worried about Arava as it is in the same class as methotrexate, but I'm not having the same troubles, thank goodness!
I can say also - if youdon't drink a LOT of water, get LOTS of B vitamin and folic acid in you regularly, the meds can do funky things to you as well. I know this is all little stuff, but combined together, it can make a difference, and anything for the better is a good thing.
I wish you well. hang in there. I hope the docs are able to help get you feeling better VERY soon. ****