Lupus caused by medications

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Regular Member

Date Joined Aug 2008
Total Posts : 233
   Posted 8/19/2008 3:44 PM (GMT -7)   
Hi all,
just wondering how many of you taking Enbrel or Humira have been diagnosed with Lupus after taking these medications?    Once you have Lupus can it go away?

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 8/19/2008 4:15 PM (GMT -7)   
You might also want to ask this on the lupus board. I have heard stories of people for whom it did go away but also some for whom it did not.
The way I look at it my immune system is so messed up that if it decided to get more messed up I doubt it would go back to "normal" afterward.

Veteran Member

Date Joined Feb 2003
Total Posts : 5514
   Posted 8/19/2008 5:44 PM (GMT -7)   
Hi Alicat,
I'm a regular in the lupus forum.  Yes, you can get what's called Drug Induced Lupus.  Once the drug is discontinued and cleared by the body, the lupus goes away.  We can talk about it more in the lupus forum if you like.  Just start a new topic about it like you did here.
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

34 years old. Diagnosed with lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, seizure disorder-(miraclulously disappeared!), Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, Cozaar, calcium, Cykolokapron, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus

Forum Moderator

Date Joined Nov 2003
Total Posts : 7121
   Posted 8/20/2008 3:01 PM (GMT -7)   
For the most part, lupus antibodies that develop while taking these meds do go away within 12 weeks of stopping the medication. However that is not always the case. Read my story:
I first took Remicade and then humira. I developed Lupus antibodies while on the Remicade and that is why they switched me to Humira. I again/continued to have lupus antibodies, had a severe reaction and was taken off humira in Dec '07.

In March, I began running a fever, my fingers became inflamed, swollen, hot to the touch and extrememly painful, and I developed odd rashes. In May my rheumy ran the antibody test again and my C3 complement and I was having a LUPUS flare. A course of steroids and when off 2 weeks all the symptoms returned and my blood tests again showed Lupus.

A very, very small percentage of people that develop drug induced lupus on Humira or Remicade go on to develop outright SLE. I believe that it is less than .001% of the thousands that have taken Remicade.

Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

Post Edited (Ides) : 8/20/2008 4:05:09 PM (GMT-6)

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