I have Crohn's and ankylosing spondylitis. My Crohn's went into remission when I was on Remicade. The Remicade helped the AS for 2 1/2 years and then it stopped working. Went to Humira but unfortunately developed drug induced lupus after only 2.5 months. Was off all anti-TNF meds for a year and the AS got progressively worse. Then I went on Simponi last June and finally once again have a better quality of life like when I was on Remicade.
I have lots of inflammatory problems in my SI joints. I have had them injected several times during the last four years. I cannot sit down when the SIs are flaring. The pain is simply too much. I also used to get lots of inflammation in the tendons where they insert into the bone. This is called enthesitis and is common in AS. The anti-TNF meds really help relieve this problem. The only other relief I have gotten from the enthesitis is from steroid injections or taking oral steroids.
If you have decent insurance and can afford the MRI, go for it! The MRI can help confirm or negate an AS diagnosis. Damage from AS to the SI joints takes a while to show up on x-ray. It can be seen much earlier on the MRI.
Moderator Crohn's Disease & Osteoarthritis Forums
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, asthma, severe allergy and a host of other medical problems.