CRP and ESR results

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Regular Member

Date Joined Jul 2009
Total Posts : 49
   Posted 7/5/2010 7:00 AM (GMT -7)   
Hi everyone. I was hoping you could help me. Lat week I got my monthly methotrexate blood tests and the doctor called me to tell me that I had to have my CRP and ESR repeated as they were elevated. My CRP was 11 and my ESR was 27. I didn't think that this was high- can someone tell me the normal boundries? Thanks!

Regular Member

Date Joined May 2009
Total Posts : 173
   Posted 7/5/2010 7:21 AM (GMT -7)   
Those values aren't that bad. ESR is considered normal for women at 14-21 depending on age. CRP values are considered normal if they're 10 or less. They are non-specific markers of inflammation, therefore their elevation may be due to something other than your RA, so it's prudent to retest in several weeks.
"What can't be changed must be endured" - unknown

DX with distal Crohn's colitis Oct 2007, predominantly in rectum
Colozal and Canasa for 2+ years - developed an intolerance
6MP - elevated LFTs after 100mg, no effect after 9 months
Currently: Remicade (Nov '09), and Paleo Diet. Not quite remission, but so much better!

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 7/6/2010 8:02 PM (GMT -7)   
Those values aren't that bad but do indicate the presence of inflamation.
My rhuemy flipped when my CRP was 50 and made adjustments to my meds when my SED was 30.

Regular Member

Date Joined Dec 2005
Total Posts : 256
   Posted 7/10/2010 3:52 PM (GMT -7)   
In my experience, the "normal range" for those attributes is not necessarily accurate. It's also possible to have several different forms of auto-immune pain, inflammation, swelling etc. without necessarily having readings outside (or very far outside) the "normal range." They can even be quite severe, particularly arthralgias, without necessarily spiking your ESR or CP.

So, just because your symptoms may not match up with what is "expected" at a given reading, means next to nothing IMHO.
Conditions: Reactive Arthritis (AKA Reiter Syndrome), Crohn's Disease, Chronic Pelvic Inflammatory Syndrome, Sacroiliitis, Costochondritis, As Yet Unknown MS-Like Relapsing/Remitting Neuropathy, and a partridge in a pear tree.

Medications: Currently not that many are taken daily, but there are many at my disposal for part-time use. Low dose pain medication, after years at high doses. Working on innovative ways of taking lesser-known pharmaceuticals and non-prescription supplements to maximum benefit.

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 7/10/2010 7:07 PM (GMT -7)   
Prior poster is definetly correct about the level of measured inflamation having very little correlation with the amount of pain, stiffness and illness a person experiences.

Veteran Member

Date Joined Mar 2010
Total Posts : 2483
   Posted 7/12/2010 7:18 PM (GMT -7)   
arthralgias- what is this? I often am surprised at how good my numbers are compared to how I feel. Then my doctor further frustrates me by beaming about my "remission"- Remission-smission I feel like ass.

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 7/13/2010 6:39 PM (GMT -7)   
My rhuemy doesn't look at the labs until after she looks at the patient symptom report (rapid 3) that all patients fill out at all appointments, and asks me how I am feeling.
After that she looks at labs to make sure my liver is okay and that I am not under reporting symptoms-she has never said-well your sed rate doesn't indicate that much pain-of course if she did something like that I might have to fire her.

Veteran Member

Date Joined Jun 2008
Total Posts : 675
   Posted 7/13/2010 9:25 PM (GMT -7)   
Symptoms should not be discounted.  When seeing one doctor my inflammation factors were always normal - despite lots of pain and fatigue.  I was beginning to feel like a nutcase.  When I saw another doctor who ran the same tests through a different lab, the results were quite different and indicated significant inflammation.  

diagnoses:  mono 1972; postviral CFS 1997; fibro 1998; UCTD & osteoporosis 2007; celiac 2009
meds: Plaquenil 400 mg, occasional low dose xanax for sleep aid, artificial tears w/ ointment at night, Advil/aspirin prn and lots of vitamins

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