The following is from the American College of Rheumatology:
"Anti-CCP antibodies are potentially important surrogate markers for diagnosis and prognosis in rheumatoid arthritis (RA), because they:
• are as sensitive as, and more specific than, IgM rheumatoid factors (RF) in early and fully established disease
• may predict the eventual development into RA when found in undifferentiated arthritis
• are a marker of erosive disease in RA
• may be detected in healthy individuals years before onset of clinical RA"
You can read the entire article at /www.rheumatology.org/publications/hotline/1003anticcp.asp
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