Just Got Diagnosed

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New Member

Date Joined May 2017
Total Posts : 2
   Posted 5/24/2017 5:49 PM (GMT -7)   
Hi everyone,

I just got diagnosed with seronegative RA, and have been on prednisone for a week, and it doesn't seem to be completely working yet. At the moment both of my knees are inflamed, though the left one is really bad that I had to get a cortisone shot done, my elbows, pinkies and wrists are also inflammed. The doctor suggested that we try plaquenil, but said it might not work for me if my inflammation is bad. We're thinking about trying Humira, and I wanted to see what you guys think. If I start Humira now do you think I'd be able to go to not as strong meds later in life, like DMARDs? And what risks and side effects have you experienced from Humira or other biologics? '

Thanks for your help,

Forum Moderator

Date Joined Feb 2003
Total Posts : 15541
   Posted 5/26/2017 5:54 AM (GMT -7)   
Katrina, with you having so much inflammation going on it is reasonable for the dr to put you on Humira. The key to this is to get the inflammation under control & hope it is caught before it does any damage to your joints.

I have crohns disease & was on Humira & I did ok with it. Please understand when we read the potential side effects, they are just that, potential. It does not mean that it will happen to you. The pharmaceuticals are required by law to list these side effects. Humira may or may not help you, you will never know until you try it. Everyone reacts so differently to medications so if someone says oh that did not help me, again that may not be the case for you.

Ask your dr about switching to something else later he will be your best source of info. Take care.
Moderator in Chronic Pain & Psoriasis Forums

Veteran Member

Date Joined Feb 2009
Total Posts : 1883
   Posted 5/26/2017 8:14 AM (GMT -7)   
Katrina, the DMARDS like plaquenil take a long time to kick in, so just be aware of that. I you have a good doc, talk to her and see what she thinks. Give the prednisone a little bit longer to see how it goes. Sorry about the diagnosis...
Sjogrens syndrome 2/15 via lip biopsy: Seronegative RA , fibromyalgia
colitis-resection 11/10, hashimoto's thyroiditis, morphea, GERD
Meds: plaquenil, synthroid, Januvia, nexium, restasis, estrogen patch, prometrium, VSL #3, evening primrose oil, Omega 3 supplement-Maxi Tears.

celebrate life
Veteran Member

Date Joined Dec 2014
Total Posts : 2089
   Posted 5/28/2017 1:07 PM (GMT -7)   
Hi Katrina,
Sorry that you have this diagnosis, but there are now a lot of meds to help. I was on guinea for over six years after the DMARDS didn't work. After starting humorous I was able to quit ALL other meds and could do everything but kneel. I even worked out at the gym.
I had no side effects. Eventually it stopped working so now I'm on Enbril, methotrexate and low dose of prednisone.

New Member

Date Joined Jun 2017
Total Posts : 3
   Posted 6/18/2017 3:48 AM (GMT -7)   
Hi Katrina, RA is new to me too. I had a rapid onset of widespread symptoms Sept 2016. From fingers to shoulders and toes to knees, very high RF and anti CCP. Lots of inflammation and pain, not much swelling. I stayed on prednisone 3 months, tapering off while starting DMARDs methotrexate, then adding hydroxychloroquine (plaquenil), and later on sulphsalazine. And some NSAIDs. Dropped the sulphsalazine again due to nausea. Still not 100% effective.
Biologics aren't offered on my country's (New Zealand) free public health system until we've tried and failed a range of DMARDs.
I've never heard that a biologic will make future use of DMARDs less potentially effective. Good luck.
RA. Subcutaneous Methotrexate, Hydroxychloroquine, Naproxen.
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