Glycine and Apigenin

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Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 3787
   Posted 9/25/2017 4:55 PM (GMT -7)   
I usually hang out in the UC forum,but I thought I would pass this info along.
Seems to me that arthritis starts in the gut. Anyway for what it is worth.
This info will get you started.
By the way even normal people are at about a 10 gram shortage of glycine a day between
food and metabolic synthesis. If you have arthritis you might even need more than 10 grams
a day as a supplement.
Old Mike

iai.asm.org/content/69/9/5883.full

shortage

/www.ncbi.nlm.nih.gov/pubmed/20093739

Apigenin fresh parsley might work better than dried
/www.ncbi.nlm.nih.gov/pubmed/18038911

Post Edited (Old Mike) : 9/25/2017 6:17:33 PM (GMT-6)


Scott007
Regular Member


Date Joined Apr 2017
Total Posts : 78
   Posted 9/26/2017 4:16 AM (GMT -7)   
Hi Old Mike,

Thank you so much for this article on the Glycine-Gated Chloride Channel in RA! I enjoy reading articles in medical science journals.

I was reading an article about UC yesterday in "Clinical Medicine Insights: Gastroenterology"
"Inflammatory Bowel Disease: An Expanding Global Health Problem"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020403/pdf/cgast-6-2013-033.pdf

This article was more about demographics than potential causes. Some notable excerpts here:

"It is now clear that IBD is increasing worldwide and has become a global emergence disease. IBD, which includes Crohn’s disease (CD) and ulcerative colitis (UC), has been considered a problem in industrial-urbanized societies and attributed largely to a Westernized lifestyle and other associated environmental factors. Its incidence and prevalence in developing countries is steadily rising and has been attributed to the rapid modernization and Westernization of the population."

"In the West, biological agents are the fastest-growing segment of the prescription drug market. These agents cost thousands of dollars per patient per year. The healthcare systems, and certainly the patients,
in developing countries will struggle to afford such expensive treatments. The need for biological therapy will inevitably increase dramatically..."

"Meta-analyses conducted in patients acquiring IBD at a young age also reveals a trend for their increased
risk of developing colorectal cancer (CRC), since the cumulative incidence rates of CRC in IBD-patients diagnosed in childhood are higher than those observed in adults."
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