Remicade & Pregnacy X-post

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New Member

Date Joined Jun 2006
Total Posts : 8
   Posted 9/18/2006 3:24 PM (GMT -7)   
Hi all,
I am posting this message here as well as on the crohn's board because folks with RA take remidace too.
I was advised to not get pregnant again after my last aggravated Crohn's Disease, which I didn't even know I had, though in hindsight, makes sense. i developed toxic megacolon and my colon was removed & the pregnacy terminated. Well, this pregnancy wasn't planned, but my crohn's has been in remission with my regular infusions of remicade, so here I am at 20 weeks and doing fine.
My qustion is for any who have used remicade while pregnant: were you able to have a vaginal birth. I came across a doctor who has a theory that because remicade is a TNF blocker and TNF helps the cervix ripen, more women who take remicasde have c-sections because the cervix is "uncooperative." This is a totally unproven theory, She has had 3 patients on remicade where it was difficult to even induce.
My other question is about breastfeeding since I am finding conflicting info on the internet and really hope to breastfeed.
Thank in advance.
Dx: Crohn's disease, antiphospholipid antibody syndrom 12/2002; ileostomy 12/2002; sleep apnea, 2006, asthma
Meds: Remicade every 8 wks; synthroid, very low dose; Lovenox while preggers otherwise coumidan; 6MP suspended while preggers; flonase; albuterol; flovent; VSL #3 probiotic
Other: saggital sinus thrombosis, 2002, with complete recovery; thyroid nodule; currently pregnant, due 2/6/2007

Veteran Member

Date Joined Mar 2005
Total Posts : 1884
   Posted 9/18/2006 8:27 PM (GMT -7)   
Hi Mizdna and welcome to HW arthritis forum!
I don't believe anyone in this forum has been on Remicade WHILE pregnant....i could be mistaken, though. I do know someone(s) in another forum (either Chron's or Lupus forum -  I cannot remember) has had a successful pregnacy while on Remicade. It is an interesting theory your doctor has, and will be interesting to see if that pans out.
I don't know the answer to the breastfeeding question either.....however, if you do decide/find out that breastfeeding while on Remicade is not the best solution, please don't let that upset you and never let any of those militant breast feeders get to you. They are awful! Your health and ability to CARE for your baby is more important than breast feeding. Trust me on this one. It's all about the time and love you give your child.  Yes, I did nurse my children - but I wasn't on the meds llike I am now at the time, I hadn't found anything that 'worked' yet so it was not an issue to stop.
There are a few people here who might have some info to answer your questions. Hopefully,they'll be around soon. Take care, good luck, and keep us up to date on what you find and your progress.

Veteran Member

Date Joined Sep 2005
Total Posts : 1744
   Posted 9/19/2006 4:21 AM (GMT -7)   

To my knowledge, there isn't anyone on this forum that has ever taken remicade during pregnancy, but I do recall several people on the crohn's forum.  One lady had two successful pregnancies while on remicade.  I know for a fact that enbrel, another tnf-inhibitor, is a category b drug for pregnancy--safe, in other words.  Not sure about remicade.  The following website gives great information about drugs during pregnancy, and breastfeeding.  There's not a whole of info. about remicade, though.  Go with your GI and OB's opinions.  You may note that according to the following website, remicade is a category C drug, and not recommended during pregnancy.  However, I have met several women who have taken remicade during pregnancy--I believe cd is one of those conditions where the benefits outweigh the risks.

Camama is right about breastfeeding.  I think it's wonderful that you want to breastfeed.  If it doesn't work out, though, whether it's due to medication or other factors, don't beat yourself over it.  Not worth it.  I wanted to breastfeed my twin girls, and actually managed to last 6 weeks, but couldn't continue.  Several friends made rather nasty comments to me; I had criticism coming from all directions.  I had even read articles that not only quoted the benefits of breastfeeding over formula, but actually implied that if you don't breastfeed you are abusing your baby!  It's largely a personal decision, and sometimes the decision is actually taken out of our hands.  My girls spent their entire first year on formula.  They are very healthy--rarely get sick--no allergies--no weird immune system function, or anything else people try to tell you when you don't breastfeed.

I honestly don't know about c-sections and the use of tnf-inhibitors.  That sounds like it's just your doctor's theory, and she is basing it on only 3 patients?  It may be what she's comfortable with, but if you're not comfortable with it consider finding a doctor who will allow you to try a natural delivery.  C-sections aren't all that bad; because I had twins, I had my choice of a natural delivery or a c-section.  I chose to try natural, and after 21 hours of labor, ended up with a c-section.  Recovery time is slower, but I bounced back with no problems at all.  If I ever had another baby (which I won't but that's another story), I would choose a c-section again. 

Best of luck in whatever you decide to do.




Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan

Post Edited (elcamino) : 9/19/2006 5:23:37 AM (GMT-6)

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