New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Aug 2005
Total Posts : 289
   Posted 10/25/2006 5:39 AM (GMT -7)   
Don't know if you all remember me or not.  But, over the last four months I have suffered severely without receiving any help from the rheumatolotists.  Was diagnosed with JRA based on past history but then the rheumy said no.  Then they were going to start me on meds based on high CRP, bone scan and MRI but then said lets wait.  Well, the wait is finally over.  I had an appt today, barely able to stand let alone walk, they found the condition has progressed/evolved and is now affecting knees, hips, and wrists alone with the longstanding ankles and feet.  Still no name for it other than autoimmune inflammatory arthritis.  They are putting me on a medrol dose pack again today stating that they want me to be in less pain when they teach me about methotrexate and start it next Tuesday.  So, finally I might have relief in the future.  Anything you guys want to tell me about methotrexate?  What is the likelihood of severe side effects? or should I just save it for the doc?
How is everyone else doing?
dx: Systemic Juvenile Rheumatoid Arthritis: otherwise known as Adult onset Still's Disease. Asthma, hypertension, hypothyroid
Meds: Indomethacin TID, Neurontin 600mg, Maxair, Advair 250/50, Diovan HCT 160mg/25mg QD, Synthroid .1mg QD, Women's One a Day,  Ultram PRN.

Veteran Member

Date Joined May 2006
Total Posts : 1179
   Posted 10/25/2006 6:03 AM (GMT -7)   
hi theresa! welcome back. sorry you have been in such discomfort for so long. glad your finally getting treatment. first the medrol pack should give you some relief soon if not already.... next you probably will be given a lesser dose to start with on the mtx and gradually build it up as your system tolerates. for me i have had little side effects. initally i had like a motion sickness and fatigue, but i know take it before bed on friday night so i sleep through all and any side effects. for me it is a true blessing. i hope it works for you. there is tons of info out there on the web. any questions feel free to ask any of us here as many either take or have taken mtx. good luck yalinda

Veteran Member

Date Joined Mar 2005
Total Posts : 1884
   Posted 10/25/2006 7:04 PM (GMT -7)   

Hi and welcome back!

Sorry you are still having so many issues. I just posted elsewhere, that folic acid is a good supplement to take when on methotrexate. And/or a good B complex vitamin. I recall that methotrexate can deplete folic acid in your body which then can contribute to fatigue caused by the medication.

I know a lot of people on methotrexate who haven't had any other issues with the med, other than being tired the day/day after they take it. Though I was told I wasn't allergic to it, I never felt that great on it. Aside from fatigue, I had constant chest/breathing issues. NOthing serious, but if I walked by someone who was smoking, I'd be hacking away for the next half hour. I had some issues as well, like dizziness, etc. but nothing serious. I didn't have HW to help with the tricks back then either! tongue ***


Veteran Member

Date Joined Dec 2005
Total Posts : 1782
   Posted 10/25/2006 9:16 PM (GMT -7)   
Hi and welcome back. I've been on MTX for over 2 years now. First on oral, now on injectable (.7 ml = 17.5 mgs, I think - soon to be adjusted up). I also take 2 mgs of folic acid daily. I experienced a few side effects on the oral (headaches, nausea, hair thinning). We upped my folic acid from 1 mg to 2 mg and switched me to the injectable. Since the switch, I rarely have any effects. I take my shot Sunday nights before bedtime. Seems to really work doing that. We added the MTX as a complement to Enbrel when the Enbrel started losing its effectiveness. It has made a big difference in my RA (it's in my hands) and I still take it even though I'm now on Remicade.

You must take prescription strength folic acid while on MTX. OTC strength is measured in mcg's not mg's and is just not enough. Talk to your doctor -- you can adjust the folic acid dosage to help alleviate any side effects you might experience without negating the MTX. Oh, regular blood tests are crucial -- I have them monthly. These are primarily to check your liver enzymes as MTX can affect your liver.

It works for some and not for others, just like some get serious and not so serious side effects. This is just my experience and I don't regret doing it, YMMV...

Good luck and I hope you feel better soon.

"My "Trifecta" - CD, AS & RA...

Co-Moderator Crohn's Forum

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, November 21, 2017 12:42 PM (GMT -7)
There are a total of 2,896,355 posts in 317,897 threads.
View Active Threads

Who's Online
This forum has 157482 registered members. Please welcome our newest member, JohnnyG113.
454 Guest(s), 13 Registered Member(s) are currently online.  Details
LymeBug21, Corvette Joe, hammer8, readingmom, Jaxy, Lynnwood, Twingirls, suttersmill, JohnnyG113, InTheShop, Shelly1978, Loquito, Pgpb

About Us | Advertise | Donate
Newsletter | Privacy Policy & Disclaimer
Follow on Facebook Follow on Twitter Follow on Pinterest
©1996-2017 LLC  All Rights Reserved.