My rheumy has told me he thinks I may have this problem as well. I've been taking the biologics (humira and enbrel), and now have added methotrexate, for my arthritis. My lower GI symptoms disappeared when I started taking the biologics (last January). I wonder what would happen if I stopped taking enbrel--I'm afraid to find out.
erin is right. Many IBDers bypass the stomach and use mtx injections. if you're already injecting a biologic, like enbrel, what's another weekly injection? I also have a sensitive stomach and was terrified to try mtx. but I take it prior to going to bed at night and I haven't had any major nausea. My appetite is suppressed a bit for a couple of days, but I can afford to miss a couple of meals :)
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan