I have Fibromyalsia, Rhuematoid Arthritis. Rhuemetologist put me on Methotrexate, gave me mouth sores, very bad sore throats and made me sick. Then put me on Enbrel. Took it once and got a severe infection in my nose. Got so bad it was in my whole face. Stopped it.took antibiotics for a month because it kept coming back. Then got back on the enbrel, sores came back. Then he put me on Humira. Took it once and had a bad injection site reaction also with a bad rash on my torso. And felt very sick. This happened a week after I took it. And still have the sores in my nose , they are gone for a few days then come back. They started in July 06. Ended up getting Pleurisy for two mos. now, and still have it. And also have a vaginal infection right now. He put me on mobic and doubled my prednisone. Seems to be helping. But what am I to expect with the treatment of the RA if I can't take the meds for it? Help...I can't stand the pain anymore. I just don't want to be crippled. Two of my sisters also have RA and already have had to have joint replacements. One sis had her elbow replaced at age 26 and my other sis had both her knees replaced in her early forties. Any info will help. Im so frustrated.