I have been off of plaquenil successfully for the past 6 months or so. I don't even miss it. I guess I was right when I felt it wasn't really doing anything for me. Rheumy, when he put me on it, did say it was one of the milder DMARDs, but his lupus patients all take it. I don't have lupus, but my arthritis is distinctly lupus-like. But since enbrel and mtx, I have had few problems.
Oh well, I guess I need to worry about getting malaria now :)
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Methotrexate, nexium, tramadol, nasonex,Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan, zyrtec, zegerid, aciphex