im HBLA27 neg.
i have stiff neck, back pain and ribs pain.
blood tests neg. no ESR nor CPR
please reply i dont know what could be? when i have bowel problems my hips hurt
did coloscopy and endoscopy no crohns
knees and hips and fingers and ankles affected.
I got seronegative spondyloarthropaty so i've read much for these type of diseases and i know plenty.
AS is a 'final diagnosis' part of the seronegative spondyloarthropaties group of arthritis.
There are 4 other 'final' diagnoses which are part of the spondyloarthropaties gropup. They are enteropathic arthritis, reactive arthritis, psoriatic arthritis and undeferentiated spondyloarthropathy and they all along with AS share 4 MAIN SIMILARITIES: primary joint surroung tissue involvment(ligaments, tendons), mild (if any) sinovitis, sacroiliac joints involvment and negative RF, ANA. Initial diagnosis of enteropathic arthritis, ReA or PsA may later develop in AS. If the doctor strictly follows the conventions then diagnosis of AS should not be established until there is no typical for AS physical sinal changes seen on x-rays like fusions, spinal erosions or growths. If the findigs are not enough to establish one of the other major diagnoses in the group - reactive, enteropatic or psoriatic arthritis but there is no physical AS changes yet then docs often use the 'undeferentiated spondyloarthropathy' diagnosis, but they do not realy know what's wrong with you and how yr disease will develop in future.
RA and Lupus arthritis are not a part of the seronegative spondyloarthropaties group, they have different clinical symptoms and blood work results. But it is not impossible a person to have both: RA or Lupus with one of the spondyloarthropaties.
There is a scientific evidence that AS is actually a 'reactive' arthritis caused by a abnormal body reaction to bowel bacteria which usually lives in our guts but however in the person affected by the AS this bacteria causes 'smth like a constant alergy' to it , and it's constant presense in the guts sets a pattern for a typical chronic ilness in the otherwise symbiotic host.
Let me remind that my spondyloarthropathy started after long lasting untrated prostate infection with the mentioned bacteria.
I'm also HLA B27 negative, so this is not a signifficant criteria. I am HLA DR4 positive which is known as one of the RA contrubutors tissue genes, but godness i don't have RA, that's pretty sure. At least 4 now. Also nobody known of my relatives has/had it. So this thing about the tissue genes is realy not cleared enough that's why tissue genes are not a main criteria for diagnosis, and are commonly not performed at all.
Official dx, but I have doubts: chronic reiter's syndrome (1yr and 6 mnths).