Joint Pain with No Inflammation??

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Regular Member

Date Joined Oct 2005
Total Posts : 315
   Posted 9/14/2008 7:37 AM (GMT -7)   
I have had the same thing happen, tests come back fine, even though I have severe pain around joints. I have even had tests come back with very visible inflammation around my ankle, and boy was it painful. But yet, the ESR and some other tests came back "fine". I also get the feeling around my joints as if they were extremely pressurized and feel like they are about to explode! And I also feel like they need to be cracked or something. Visually it reminds of blowing up a balloon just as it reaches the point of popping. Sometimes I wish I just stick a pin in my joints and let the pressure out. When I'm that achy and pained, though, my joints won't crack, even if I try.

Veteran Member

Date Joined Feb 2007
Total Posts : 553
   Posted 3/20/2009 12:12 PM (GMT -7)   
idea  I also have joint pain with very little or no swelling.  Sometimes I can see a redness around the joints in my fingers when they are hurting, but they have never been more than mildly puffy.  When my joints get really bad it feels like there is 'crud' in the joint- and if I could just take it apart, clean it out, and put it back together clean it would be all right for a while.  Other times I feel like it needs to pop so bad that it might just make it feel better to break it and just let it heal without the pressure.  (Yes, I am aware that all of these are BAD ideas.) 
I don't know if I have had the ccp test, but when I had the Rh test done in Feb '08 it was really high.  (I wanted to write the # here- but I don't remember it!) I haven't had x-rays done since I was first brought in to the office about a year ago, but at the time I had much less joint pain daily.  I guess it has turned aggressive since then.  They didn't show any evidence of RA at he time, I wonder if it would be different now.
Current medications:
Bipolar treatment-Lamictal, 200mg, Mood stabelizer, daily(main side effect: brain fog) Bipolar treatment-Cymbalta, 40mg, Antidepressant, daily(main side effect: GI upset, decreased clotting, insominia) Anemia, Fatigue treatment- Iron supplement, 65mg, daily(main side effect: constipation) Insominia treatment- Ambien, 10mg, daily(main side effect: amnesia eppisodes between taking pill and falling asleep) Mania treatment- Alprazolam, .25mg, Very rarely(main side effect: fatigue, slowing of thoughts, depression of CNS, can't take ambien or vicodin when on it) RA treatment- Plaquenil, 400mg, daily(main side effect: GI upset, decreased clotting) RA treatment- Methotrexate, 25mg, 1X weekly(main side effects: hair loss, stomach upset, mouth sores, sore muscles, fatigue, brain fog, compromised immune system, decreased Folic Acid absorption) GI upset treatment- Leucovorin Calcium, 10mg 1x weekly(main side effects: ?) Folic Acid defintioncy- Folic Acid, 1mg, daily(main side effects: ?) RA treatment- Prednisone, 8mg(and decreasing...)daily(main side effects: increased manic eppisodes, constipation, brain fog, bone density degeneration, compromised immune system) Multi-mineral Supplement (main side effects: constipation, GI upset) Constipation treatment- Docusate Sodium, 200mg, daily(main side effects:?) pain control- Motrin, 800mg, PRN Q6hours daily(main side effects: GI upset, decreased clotting) Pain Control- Vicodin, 5-500mg, PRN Q12hours regularly (main side effects: brain fog, fatigue)

New Member

Date Joined Apr 2009
Total Posts : 2
   Posted 4/7/2009 1:48 PM (GMT -7)   
There are a lot of medical treatments readily available for joint pain problems. Hence, trying out the natural way may not be harmful to both the budget and health. There are also a lot of natural ways in treating common joint problems, however only a few pursue in using it all the way. There are online sites that can help us understand more of those innovative natural ways. A little sacrifice in reading and scanning through web pages can be of great help.
Steve Butler

jonny gorg
New Member

Date Joined Apr 2009
Total Posts : 1
   Posted 4/8/2009 6:19 AM (GMT -7)   
i am sufferring from joint paint since last 2 years.I have done RF test which came out to be positive, but when i went to a rhumatologist he made me do CPP test which came out to be normal.Hence he also made me do SGPT test whose number was quite high and was shown as 243.
The sign of this pain is not good as i have stiff joints in the morning and the joints also hurt all day long.
can my high SGPT be the cause of it?

New Member

Date Joined Dec 2012
Total Posts : 2
   Posted 12/7/2012 10:08 PM (GMT -7)   
Yes..its possible to have non-inflammatory joint pain. Many people do not have muscle pain or tender points, its just the excruciating joint pain.
Lewis Orthopaedics

Veteran Member

Date Joined Feb 2009
Total Posts : 1880
   Posted 12/9/2012 8:16 AM (GMT -7)   
Mandolen, I saw where you have crohn's. Do you go on the crohn's forum? A lot of people with IBD get inflammatory arthritis. It just goes with the territory I am sorry to say. I had inflammation in my intestines and I ended up with inflammatory arthritis too but I had positive tests. I hope your pain gets better soon and that the docs can do something for you. Don't give up.
d 1/09 with colitis sigmoid colon with some diverticular disease as well, Colon resection Nov. 2010, now in remission!
seronegative RA, type 2 d, asthma, skin scleroderma, VSL#3 probiotic, Vit. D, nexium, synthroid,
Positive ANA speckled pattern 1:180, high sed r

New Member

Date Joined Oct 2017
Total Posts : 1
   Posted 10/19/2017 5:02 PM (GMT -7)   
I have joint pain in my hips, ankles, wrists , finges toes. It gets to the point where theres days I can't even move. I was put on prednisone for 10 days had no pain at all until I was done with med and then the pain started to come back so my Dr. Order blood work it came back with a Ra factor of 10 , Sed rate of 2 and ana negitive. If the steroids completely took away my pain isn't that a huge sign of RA and inflamation. How do I come back showing to have neighter?

Forum Moderator

Date Joined Feb 2003
Total Posts : 15177
   Posted 10/20/2017 9:44 AM (GMT -7)   
Hello Bets I happened to see your post & welcome to Healing Well. . So sorry to read that you are struggling so much. If you do not have a diagnosis of RA, I suggest that you ask to be referred to a rheumatologist for an evaluation. Preferably one that specializes in RA if possible. A GP is not a good source to make an official diagnosis.

Usually a GP will order an ESR/sed rate & CPR for labs, along with ANA testing. None of these are used solely to make a diagnosis for RA, they are just tools to see what is going on. People can have a positive & negative ANA & have nothing wrong. Steroids are used for all types of inflammation in the body. They should not be used long term because of the side effects.

A good rheumatologist will run his/her own set of labs including including what you hve already had done. These labs will be much in depth than what your GP ordered, such as an anti-CCP antibodies & many others. Imaging is often done to check for joint issues.

I know it is frustrating not having an answer, however, there is nothing wrong with advocating for medical care. Now a days we often have to do this to get the care we need.

Take care.
Moderator in Chronic Pain & Psoriasis Forums
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