Strong family history of cancer and Enbrel

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New Member

Date Joined Dec 2007
Total Posts : 8
   Posted 12/1/2007 5:48 PM (GMT -7)   
I have been on Arava, Imuron and Methatrexate with absolutely NO relief.  My rheumatologist is recommending I go on Enbrel but I'm concerned because I have a strong family history of cancer. 
Is Enbrel recommended if there is a strong family history of cancer? 
Your input on this issue is greatly appreciated! 

Veteran Member

Date Joined Dec 2005
Total Posts : 1782
   Posted 12/1/2007 9:35 PM (GMT -7)   
Is Lymphoma one of the cancers that runs in your family? If so, I would definitely talk to the doctor about it. I have cancer on both sides of my family, Lymphoma is not one of them. I was on Enbrel, switched to Remicade and most likely will be on Humira pretty soon. I started with the Enbrel about 4 years ago. So far so good.

The cancer issue is a real fear and I understand it. What decided it for me, after I had a long talk with my rheumy, was quality vs. quantity of life. As scared as I was, the Enbrel worked wonders for me (as did the Remicade).

I was able to get on with my life and do the things I wanted to - that alone was worth the risk, for me. Talk to your doctor and then make your decision. Good luck.

Some days you're the bug, some days you're the windshield

RA, AS, intolerance/sensitivity to gluten, wheat and dairy.

Remicade every 6 weeks, Methotrexate weekly, Folic Acid daily

Veteran Member

Date Joined May 2006
Total Posts : 1179
   Posted 12/3/2007 4:47 AM (GMT -7)   
hi roja, i am not expert but the way i understand it is .....
it is not understood if our medications increase our risk for cancers or the fact that many of us have autoimmune systems that attack us incorrectly. i have RA and all my meds including enbrel list cancer as a possible side effect but my rhuemmy told me RA may be linked to the cancer, and not the the treatments. i also think the types of cancers in your family might matter? lung -smoking related or breast - hormone induced type etc......
i think when erin gets back she will explain it more clearer?
good luck in your search for information. yally

New Member

Date Joined Dec 2007
Total Posts : 8
   Posted 12/5/2007 8:10 PM (GMT -7)   
Thank you for the response regarding the use of Enbrel and a family history of cancer.  I believe I have reached the point with my RA that I need to take something that provides some relief from the pain and restriction on movement the disease has caused.  
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