Enbrel is a wonderful drug, but works for me only when combined with mtx. I started on enbrel, and didn't receive full benefits until about 5 months into it. I felt some effect earlier than that, but it took maybe 3-4 weeks to do so. It wasn't until I added mtx that I was getting the complete benefit from both drugs. Other people tell me that 2 weeks was long enough for them to feel enbrel's effects. I guess everyone's different--I'm just a slow responder.
Best of luck,
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan