Yes, of course you can have inflammation and irritation without having an infection.
Have you tried using a sinus medication for relief? I generally use Pseudo-ephedrine Hydrochloride (CVS has it's own brand behind the counter) - it's a nasal decongestant that helps sinus pressure. I take this along with some Ibuprofen for the inflammation.
I actually don't know if my facial sinus pain is associated with my Sjogren's or not, but this treatment seems to take care of it.
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2002DIAGNOSING LUPUS & HW's LUPUS 101
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