Hi fnfiacco. The antibodies that are positive for Sjogren's are SS-A and SS-B and the test methodology (ELISA) is usually very specific for just those antibodies.
The centromere antibody test is usually run to help diagnose or rule out CREST or scleroderma and to my knowledge it is not at all useful in diagnosing Sjogren's.
I wish I had better information for you. Lots of folks have chronic dry eyes and if over the counter medications don't help, you may consider seeing an ophthalmologist (a physician who specializes in the eyes). Love, Butterflake
SLE '05, Sjogren's, Fibro, Raynaud's, major depressive disorder, CVID (Common Variable Immunodeficiency), Hypertension, Osteoporosis, CNS problems, GERD, angina, 1st stage kidney disease. Many meds: better living through chemistry