Do meds = weight gain?

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New Member

Date Joined Jun 2008
Total Posts : 18
   Posted 6/23/2008 1:26 AM (GMT -7)   
Is it just that they increase appetite or do the meds actually change the way you metabolize food? Sometimes I feel as though no matter how little I eat or how well I eat, the weight doesn't fluctuate much. And then I see other people chowing down hamburgers and milkshakes all the time..... It's so frustrating!

Am I doomed to keep gaining and gaining weight? I'm not even on that many meds, or even meds that are deemed to have that side effect. (I take some type II diabetes meds, zoloft, and lamictal) But as I'm just recently dx'd, I'm sure more meds are going to be added to the med "cocktail". (And darn the prescription costs! Sheeesh.... Lamictal $200????)

Veteran Member

Date Joined May 2007
Total Posts : 3715
   Posted 6/23/2008 7:05 AM (GMT -7)   
Hi Ankh,

Some meds actually increase your appetite, I know that much. I don't know about the change of metabolizing food. That's an interesting question. You should ask your doctor. In any case, the doc knows which meds are "weight neutral" and if you tell him/her that you're concerned about that, you can avoid the meds that really cause weight gain.

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Bipolar II

Georgie Girl
Regular Member

Date Joined May 2008
Total Posts : 319
   Posted 6/23/2008 7:18 AM (GMT -7)   

Hi Ankh

Some meds are weight neutral - my doc said that Lamictal is weight neutral and I found that to be true.

However, I gained 15 lbs in 6 weeks on Zyprexa and Depakote and from what I've read, I'm lucky it's not more. I find that I am always hungry.  I have also read that these meds actually change your metabolism to cause weight gain but I would say my gain is a result of being hungry every waking minute. 

It's particularly discouraging because early this year I worked very hard and lost 20 lbs over 8 weeks then I regained 15 of those pounds.

Good luck to you.




Georgie Girl

New Member

Date Joined Jun 2008
Total Posts : 18
   Posted 6/23/2008 1:41 PM (GMT -7)   
How unfair. To think that we suffer from some type of mood disorder/depression and gaining weight is not something to perk up your mood in the least bit.

What does klonopin do? Is that weight neutral?

I have diabetes and gaining weight is not just an aesthetic thing, it's not good for my blood sugars either. confused

Ellie 1
Veteran Member

Date Joined Apr 2005
Total Posts : 1291
   Posted 6/23/2008 7:21 PM (GMT -7)   
I believe Klonopin is weight neutral, Abilify is another that doesn't cause weight gain. In fact, in the last 18 months I've lost 40 pounds.
I began with my pdoc telling him that if possible I wished to take nothing that would make me gain weight and he's been really good about keeping those meds as a last resort.
Good judgement comes from experience and alot of that comes from bad judgement.
You just have to accept that some days you're the pigeon, and some days you're the statue. 

olivia of course
Veteran Member

Date Joined Jul 2006
Total Posts : 1523
   Posted 6/24/2008 3:06 PM (GMT -7)   
At the same time, some people still gain weight. Even though Lamictal is weight neutral, I gained about 30lbs when I was on it. I was also taking 300mg a day that might have played a role.
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Regular Member

Date Joined Mar 2008
Total Posts : 82
   Posted 6/25/2008 12:56 PM (GMT -7)   
Depokate is a big weight gainer from my experience.. I put on 50 lbs..
Having a hard time losing it as well......
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