There are other mood stabilizers out there and not every one works forever...some have better luck with depakote than others. If you have a psych you trust, I would definitely go to him/her and talk about your options. There's always hope.
Lithium; Clonazepam; Ativan
Bipolar, panic disorder, PTSD, PCOS, hashimoto's disease/hypothyroidism, and in the process of being diagnosed with crohns. Too many meds to list!