I don't know anything about your vascular disorder, but I do know that when you take even an aspirin a day which is a simple blood thinner, you have to discontinue at least a week before any surgical or test procedure which causes bleeding. When I had my reconstruction I was given two units of blood that I had stored before surgery. So there is a great loss of blood.
With the family history you have I think I would do anything to help keep the breast cancer at bay. Unfortunately clean margins, etc. today still can mean recurrence in the future. With breast cancer there is no certainty of cancer free forever. I have passed 12 years without recurrence, but my daughter only managed eight years, we were both clear for those years. I am not saying that to frighten you, but to tell you to be extra vigilant in your exams, tests, etc. Incidently my daughter has a degree in fashion design but she worked in the manufacturing end and now is more into marketing.
Hope you will keep in touch. Hugs MK