Vioxx v. Celebrex and Bextra....

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Veteran Member

Date Joined Jul 2003
Total Posts : 892
   Posted 10/19/2004 8:39 AM (GMT -7)   
 I'm one of those who took Vioxx for a number of years for osteoarthritis.  My PCP recently switched me to Celebrex.  I'll be honest, I filled the rx but have not taken a single pill.  After days of mulling and "noodling" this around in my head, I've decided to skip the Celebrex all together.  I'm going to just take Aleve. (in a couple of years there will probably be something wrong with that one too.  Vioxx and Celebrex are once a day drugs.  My PCP told me that Bextra is 2x's a day.  I don't know what the right answer is here or if there even is any right answer at all.  I just know that I'm more comfortable taking Aleve OTC than getting involved with another drug.  I called my cardiologist and am waiting for a call back re: my new plan.  Just this morning on the TV "crawler" there was an announcement from Pfizer that they've decided to fund a clinical trial to test Celebrex and its effects on heart function.  Hmmm, one more ingredient to go into my "noodling" soup.  Hugs all, Luci
In the depth of winter, I finally learned that within me lay an invincible summer.  Albert Camus

Regular Member

Date Joined Aug 2003
Total Posts : 248
   Posted 10/19/2004 9:30 AM (GMT -7)   
Luci, I heard that story about Celebrex, too.  I also heard one about an investigation of Bextra.  I am takeing Bextra for my rheumatoid arthritis. The truth is, if aspirin was first marketed today, it would never pass the stringent FDA regulations for release! Any medication you take has risks associated with it; it's better that hurting! Hope the aleve helps! Hugs, Frayda

Regular Member

Date Joined Aug 2003
Total Posts : 106
   Posted 10/19/2004 11:16 AM (GMT -7)   


I actually take Celebrex 2x a day (200mg each). I had been on it once a day for arthritis, but my onc said that bc trials are showing that it is being tested as a prevention in bc recurrence. I'm still on it and haven't called his office to see if he's changing his view or not. I feel like we're da***ned if we do and da***ned if we don't. Sure wish we all had some answers.

Hugs, Rozanne

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Date Joined Jul 2003
Total Posts : 1106
   Posted 10/19/2004 11:20 AM (GMT -7)   
Ladies, I am on Bextra also. I have heard some things about celebrax too. I would not doubt at all that Bextra will soon be considered the same as they are all in the same drug category. I know that Vioxx sent my blood pressure sky high and I never had high blood pressure before that. My Dr took me off it because he was worried I would have a stroke. Of course, Vioxx is the one that worked the best for my pain, but Bextra comes close. Whaddya do??? I get to the point I can hardly walk if I don't take something and nothing else I have tried (which is a lot) works. If you discover anything, please let me know! =) Love you all, Gail

 It's only when we truly know and understand that we have a limited time on earth -- and that we have no way of knowing when our time is up, we will then begin to live each day to the fullest, as if it was the only one we had.   Elisabeth Kubler Ross

Veteran Member

Date Joined Jan 2004
Total Posts : 693
   Posted 10/19/2004 5:58 PM (GMT -7)   

eyes  Well for what it's worth......

I have an unstable spine due to a spinal surgery that went bad. Was supposed to get corrective surgery but got BC instead. I never got my spine fixed. I also have degenerative disk disease and alot of arthritis. To make this even better I can't take narcotics because I get violently ill from them...

I take 550 mg of Anaprox (RX version of Aleve) twice a day. I have to take OTC Zantac with that to protect my stomach. I also have a non-narcotic muscle relaxant called Skelaxin that I take twice a day.

On REALLY BAD DAYS (like when I can't feel/use my leg) I take the pill version of Toradol which is the strongest anti-inflammatory out there.

It is not perfect but it gets me through the day!

Now along with studying Celebrex as a cancer preventative- they are also studying non-steroidal anti-inflammatories (Advil, Aleve). Apparently they block prostaglandin production to reduce inflammation and over-production of prostaglandin is thought to encourage tumors to grow.  ( I am sure I have not spelled a few of those words right!)

So you might ask your docs about that if you are worried about these new tests coming out and Celebrex and Bextra being pulled off the market.

I have to add that I also take vitamin E, C and Bromelain for pain and anti-inflammatory effects too.


Veteran Member

Date Joined Jul 2003
Total Posts : 734
   Posted 10/19/2004 6:13 PM (GMT -7)   
Well, I'm still on the 200mg. twice a day too Rozanne. Nobody is going to get it away from me without a fight. Hugs, Di

Veteran Member

Date Joined Sep 2003
Total Posts : 1373
   Posted 10/19/2004 7:41 PM (GMT -7)   
I was on vioxx for the occasional flare-ups.  When my doc changed me to bekstra, I was talking to the shrink I work with about it, our resident cynic.  He thinks it's probably a drug effect, not a class effect, meaning vioxx does it and not celebrex and bextra.  We were thinking about the comparison of zyprexa and weight gain, and how they all of a sudden started (paying for and) studying the other atypical anitpsychotics when zyprexa patients were reporting all that weight gain, and they concluded that all the drugs in that class caused the weight gain, only we never see it with the others, just with zyprexa.  In other words, ladies, it's big business trying to get the others to share the blame.  Just a cynical thought, but worth sharing.  I'll stick with beckstra, because anaprox doesn't help, and the vioxx was great, so I'm hoping the beckstra will be as good.  Haven't needed it yet, thankfully. 
"Our greatest glory is not in never falling, but in rising every time we fall." -Confucius


Veteran Member

Date Joined Jul 2003
Total Posts : 702
   Posted 10/20/2004 6:44 AM (GMT -7)   
Hi Luci

As you know, a few weeks before Vioxx was taken of the market, my Dr wouldnt refill it. Last Thursday she gave me a RX for Celebrex. I havent gotten it filled..just not sure what to do.
I take Oxycontin and Oxycodone for pain, but the Vioxx really helped my hip pain. They
sure dont make this easy.....


Sometimes it is a slender thread, Sometimes a strong,
stout rope; She clings to one end, I the other;
She calls it friendship; I call it hope....

Veteran Member

Date Joined Jul 2003
Total Posts : 2044
   Posted 10/20/2004 9:06 AM (GMT -7)   

The last time I saw my PCP I asked her about Celebrex, Vioxx, etc. and she flat out refused to perscribe them. Too hard on the liver, she said. So, it's Aleve or Motrin for me. Cathi, you are so right, they don't make it easy. Hugs to all who hurt, Lauri

"Go confidently into the direction of your dreams. Live the life you always imagined" Thoreau
Life is not measured by the number of breaths we take, but by the moments that take our breath away.

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