Wow, I am not sure about that... I had the older test done in 2001, which I guess would be the IHS, and was 3+++. I was randomized into the control group and was not supposed to get Herceptin, which I was not happy about. I ended up leaving my med onc at Duke (with his blessings, since he could not give me Herceptin off study) to go to a med onc in private practice that would give me Herceptin for 1 year. Personally, I think that saved my life. My cancer was Stage IIB, 4.5cm Er-/pr- with 5 of 49 nodes positive.
With that said, you can guess what my recommendation to you would be...get the Herceptin. But only you can make that decision for yourself.. but don't let one Dr. dictate your treatment. YOU are ultimately in charge, and if you don't get into that study, there may be another one somewhere else. Or, like me, forget the study and just find another Dr. to get the best treatment possible.
good luck-- Stefanie
"It's been worth everything I've been through,
To do what I do"
To Do What I Do -Alan Jackson, 2004