I've had options 3 and 4. #3 damaged my liver and it will never fully recover. I had #4 for 15 months. It seemed to do the trick for me and I'm 9 1/2 years out from dx the first time.
I do have a problem with your post though. Who's the doctor here, you or him? He can't be worth his fees if he can't analyze your condition and decide on an appropriate treatment. I find this a little scary, MD Anderson or not. A second opinion may be necessary.
Ask him what he would do if it was his wife or daughter? Sounds like a game show, do you pick what's behind Curtain #1, Curtain #2, Curtain #3, or Curtain #4? I think he's an idiot and if what you decide doesn't work, he can always say it wasn't his fault. A lot of doctors today are like a lot of lawyers today and they should all be used to repair the levees in NO.
Stepping down from the soap box, Jo-Ann
A good friend will bail you out of jail...
but a true friend will be sitting
next to you saying,
"Dâmn... that was fun!".