EBV can often be associated with Lyme disease. I suggest seeing a Lyme Literate MD and getting tested through IgeneX lab so you know whether or not to rule Lyme out. Make sure the doc tests for co-infections, including mycoplasma, as it can be overlooked. Routine tests for Lyme through Labcorp, etc. do not yield as much information. Tests for Lyme are antibody tests, and are unreliable 60% of the time. However, the IgeneX test shows more information, and a Lyme Literate MD is trained in its interpretation.
In my opinion, CFS is a result of mitochondrial dysfunction. A doctor would have to code treatment for CFS under mitochondrial dysfunction in order to get insurance to cover it.
Any neurotoxin mediated illness can cause CFS symptoms, as the symptom set is common to a number of different diseases. (The same is true for the fibromyalgia symptom set). Lyme, Mold toxins, heavy metal toxicity, Ciguatera (Florida), and Pfiesteria (parts of Maryland and Delaware) all cause CFS symptoms (I'm sure there are more I'm missing). Electromagnetic radiation from cell towers, cell phones, antennas, wifi, smart meters, etc. can contribute to fatigue.
Best wishes, and feel free to post on the Lyme forum, too!