Is Gilbert syndrome a new risk factor for breast cancer?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

zandor
New Member


Date Joined May 2008
Total Posts : 15
   Posted Yesterday 2:32 PM (GMT -6)   
http://www.ncbi.nlm.nih.gov/pubmed/21636218 said...
Abstract
Patients with Gilbert syndrome have an impaired function of the enzyme UGT1A1, responsible for the degradation of 4-OH-estrogens. These elements are produced by the degradation of estrogens and are well-known carcinogens. In theory, patients with Gilbert syndrome accumulate 4-OH-estrogens and, therefore, might have a higher risk for breast cancer, especially when exposed to higher levels of estrogens. If this theory is true, a new risk group for breast cancer would be described, producing new insights in breast carcinogenesis.

[url]http://www.ncbi.nlm.nih.gov/pubmed/21636218[url]




it seems gilbert syndrome can be worse than i thought

sad
New Topic Post Reply Printable Version
Forum Information
Currently it is Thursday, June 21, 2018 2:10 PM (GMT -6)
There are a total of 2,974,181 posts in 326,158 threads.
View Active Threads


Who's Online
This forum has 161234 registered members. Please welcome our newest member, hennaheather.
415 Guest(s), 14 Registered Member(s) are currently online.  Details
Froggy88, imagardener2, hennaheather, sandyfeet, LucyDog, GuitarGERD, Darla, nepol, UC_from_39, mtm1704, suttie, danikacs, elvin, Tall Allen