Low IGG's and sick but told I don'tneed immuglogulin

Welcome to the autoimmune disease etc. site. Its a good thing your not satisfied with just one diagnosis because the majority of us with CFS or any form of autoimmune disease have at least 1 other diagnosis', I have 6 medical and 2 mental. And finding the "root" illness is of the utmost importance even though it may never happen. Unfortunately Dr.'s just aren't that open minded or correctly trained to notice let alone treat anything outside there very small area of "expertise." This may seem out in left field but I would suggest looking into Celiac Disease or a Gluten/Wheat Allergy. I say this because this can cause all of you symptoms plus many, many more. I am only just finding out that 90% of my stomach/intestine issues are damage from this and 50% of my CFS symptoms, some of my pain issues all can be traced back to these food allergies. Hope this helps, Keep in Touch.

---

Crainiotomy Lg. Meningioma Dec.02, Bi-Polar 2004, SMI 06, Gluten/Wheat/Dairy Intolerance, IBS 06, Migraines w/pseudo-seizures 07, Dev. Septum Sur. Sept.07, 2nd Men./Tumor Gamma Knife Rad. Dec.08, Radical Hysterectomy Sept.09 w/instant Menopause, Fibromyalgia 09, Disability since 09, EBV/CFS 11,Vomiting/Multiple Ulcers, Vertigo 12, Chronic Fatigue Moderator 2013.No meds list I ran out of space.

Hello,


I have the following lab abnormalities:

- Low IgG1 and low IgG3 (total IgG is "normal"
- Low C3 (with normal C2,C4,& CH50) of the "complement system/pathway"
- Low total IgM levels (Total IgA and IgG were normal)
- Low Vitamin D level

SYMPTOMS (these are the main ones, but I have MANY):

- full-body dysesthesias/nerve pain
- chronic recurring infections (ears, nose, throat, and lungs)...I know this is due to low IgG1, IgG3, IgM, C3, and vitamin D
- bone pain in hips...feel arthritic all over
- intolerance to heat/cold
- MSG, aspartame, gluten...etc gives me irrational rage and makes the nerve pain worse...could be autoantibodies against Glutamate Receptors (NMDA, AMPA, or kainate....or possibly a channelopathy)

- and MANY other symptoms

I figured most of this out on my own. MOST doctors are dumber than dirt and won't help me.

What I think is going on (based on what I currently know...but I will keep learning....won't give up):

I think what is going on could be one of the following, or some combination:

- some form of cancer
- autoimmunity (immune-complex disease), channelopathy, and/or Glutamate Receptor autoantibodies
- Infection

This is an oversimplification, but I will explain more if you would like.

***This all started with me when I was 27 years old. I am currently 31 years old.

I received a ridiculous amount of vaccines at that time. I got the vaccines and worked in rural South Korea for a year. I was sick the whole time in South Korea. Therefore I don't know if it was the vaccines that caused the problem...or if I picked up an infection in South Korea. I also had smoked cigarettes for 8 years...that is why I thought cancer was a possibility because it can cause autoimmunity known as "paraneoplastic neurological disorders".

Here is a synopsis:

- cancer could be causing paraneoplastic disorder because I was a smoker
- I could have an infection(viral, bacterial, fungal...etc.) from South Korea...this would explain weak immunity..and some pathogens trigger autoimmunity........I HAVE SIMILAR GENETICS AS YOU...AUTOIMMUNITY RUNS IN MY FAMILY

We should compare notes. The doctors are going to let us suffer and/or die prematurely.

Keep your spirits up. I know how you feel.


- B. G.

I'm anxious to the new rounds of blood tests results next week
I hope they find something the not knowing is killing me! Mentally I'm drained from all of this!!