For the longest time, I have days where I get very tired and mostly I am generally tired. I have fibromyalgia and chronic fatigue syndrome. My doctor has taken a comprehensive blood panel and ESR. My ESR level is 53. A couple of months ago, it was around 20. I realize that the higher the ESR level, there is more inflammation of the body causing both pains and being tired. I used to be on all types of pain meds and over the years, I don't take nearly as much. I learned to live with the pain but my being tired causes me to just not want to do much. It feels that my body just doesn't want to work and I feel unmotivated. Could all these things I have mentioned be due to high ESR? Thanks for your input.