I would also like to know this. I've been addicted to many things in my 44 yrs, and still have some addictions now. At one point I decided to clean up my act totally, and my symptoms just got worse. I self medicate too oftrn and I'm aware of the fact that I shouldn't, but I am miserable, physically, and I am sure we are not the only ones who have had problems. C'mon, we know we are not alone. But is it proven that prior substance abuse has anything to do with CFS or fibromyalgia?