Carbohydrates and Oxycontin

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Veteran Member

Date Joined Sep 2005
Total Posts : 535
   Posted 1/15/2008 6:21 PM (GMT -6)   
Hi everybody,

I hope everyone is doing well.

I've got a question, I don't remember if I have asked this before or not but does anyone know if sugar or high carbohydrate foods can increase the effects of oxycontin? I remember reading that what you eat or drink (Not including Alcohol) shouldn't have an effect on the medication but the reason I ask is I am experiencing something very odd and unnerving to say the least.

If I take my pain meds on an empty stomach I can feel them kick in but not anything too dramatic as it has always been. Now if I eat something sweet or anything with high carbohydrates within a few minutes it seems to make the pain meds stronger. I'm unsure if this is what is happening or not but it sure feels like it. I become super drowsy, Sometimes there is nausea, headaches and dizziness as well. It is the strangest thing.

This has been going on for awhile now but it's been really bad for the past couple of weeks. So bad in fact that my short term memory is the worst it has ever been. I do something an five minutes later I forget what it was I was doing. I also have been dealing with trouble concentrating and thinking. My vision is also going blurry (I just had them examined and all was normal) as well and all I want to do is sleep. Then another strange symptom I've been having is breaking out into hot, cold sweats and abdominal pain after I eat something.

Now I know that these symptoms also happen with diabetes but I do not have any of the major symptoms of diabetes. IE; Excessive thirst, frequent urination but then again not everyone with diabetes develops those symptoms. My diet could be better but I do exercise. Unfortunately, it doesn't seem to be helping with these strange symptoms.

Does anyone have an ideas or experienced something similar? I have had it with this darn pills and pain or not I can not continue to feel like this.
I am so close to telling the pain clinic no more pills. If I could come up with a taper plan myself I would do it. Then again it may not be the opioids but I suspect that they just might have something to do with all of this.

Post Edited (quahog) : 1/15/2008 7:41:59 PM (GMT-7)

Regular Member

Date Joined Dec 2007
Total Posts : 450
   Posted 1/15/2008 7:39 PM (GMT -6)   
Were you put on any other new medications? Other things that will potentiate (make stronger) this medication besides alcohol are tricyclic antidepressants, MAOIs, other central nervous system depressants, anticholinergics (reduce spasms of smooth muscles like Lomotil for diarrhea), phenothiazines (tranqulizer or antipsychotic medication), and muscle relaxants.

Honestly, I have not heard of sugar or carbs increasing the medication...but I am certainly no expert. Perhaps you could call a pharmacist to see what else could be causing it?
Mochiah/a.k.a. Sue
cervical fusion 2006, with great result
L4-5 surgery with cages, plates, and screws in 2005, I have continued pain 
MEDS:  Fentanyl patch, Norco, Celexa, trazodone, and Parafon Forte
Im going to smile like nothing is wrong, act like everything is perfect, and pretend its not hurting me.

Pete trips again!
Veteran Member

Date Joined Nov 2006
Total Posts : 1899
   Posted 1/16/2008 9:12 AM (GMT -6)   

You don't say how much or how long you have been taking oxycontin but there are several other thingg that could be causing these symptoms. I am no doctor and am only speaking from my own experiance. It could be you are having problems with your thyroid glands. I had mine removed over 10 years ago and without medication I get symptoms like you are having. Females tend to have thyroid problems more than males so it may be something you should have checked. Another problem that comes from long term use of narcotics is changes in production of hormones. In my case it's low testosterone, this problem and it can cause all kinds of horrable symtoms. My doc's are not sure why I have "Hypogonadism" either from my prostate cancer surgery or from years of pain control with use of narcotics. I don't know if females get simmilar hormonal problems from long term use, maybe someone can add to this. I would certanly have it checked out by a good Endocrinologist? I' not sure I selled that right? Dr. that deals with glandular problems including thyroid and diobetes. I hope this may help.Good luck!!

Your friend,


54 years old, Surgury, Radical Prostatectomy 8/20/03, PSA 6.6, Gleason 3 + 3 = 6, Adenocarcinoma extent (moderate) Stage & Margin:T2NOMX, No Metastases, Organ Confined, bone scan: Neg. Testosterone Theropy since 12/06. I am's what I am and that's all that I am!!! 

Regular Member

Date Joined Oct 2007
Total Posts : 92
   Posted 1/16/2008 1:13 PM (GMT -6)   
I don't know about sugars and carbs, but Grapefruit juice can affect the effects of opiates. I found that out the hard way. I had a cold a few months back and I was drinking tons of grapefruit juice I kept getting high from my meds. I asked a pharmacy student about what was doing it... They said that gf juice reduces some type of acid in your liver that breaks down opiates, thus causing more time to absorb the meds. odd huh?

Regular Member

Date Joined Jul 2006
Total Posts : 495
   Posted 1/18/2008 1:24 PM (GMT -6)   
My personal experience with my soma and percocet is that when taken on an empty stomach, and not followed by food is that they tend to take forever to actually kick in. If I take the medications and then shortly after eat anything (say 15 minutes after taking the medications) the medication then kicks in full force. If I eat and then take the medications they also seem to take a while to kick in.

If you are having problems with it kicking in too strongly - try eating before you take them. Part of the problem with taking them on an empty stomach and then eating is that your stomach starts producing the acids to breakdown the food sometimes before you take your first bite - and at that time the only thing in your stomach for it to dissolve is your medication.
"When we come to the edge of the light we know, and are about to step off into the darkness of the unknown, of one thing we can be sure; either God will provide something solid to stand on... or we will be taught to fly.'"

"Cause when push comes to shove You taste what you're made of, You might bend, till you break Cause its all you can take; On your knees you look up Decide you've had enough, You get mad you get strong Wipe your hands shake it off, Then you Stand" From "Stand" by Rascal Flatts
Dx.: Polycystic Ovarian Syndrome, Ulcerlative Colitis, Chronic Inflammation of the Colon, Ruptured & Fused L4-L5-S1 w/pinched nerves, Degenerative Disc Disease, Chronic Costochondritis, Back Muscle Spasms, Asthma, Benign Tremmors (hands)

Doing Much Better
New Member

Date Joined Jan 2008
Total Posts : 2
   Posted 1/21/2008 10:12 AM (GMT -6)   

Yes, taking sugar with Oxycodone will definitely give a rush under the right circumstances. Chocolate will really give a kick to the uptake absorption of Oxycodone into the bloodstream. Oxycodone is usually but not always a time release medication that is supposed to be released in the body in the small intestinal tract similar to any other time released meds. Next to alcohol, simple sugars are absorbed into the body the fastest and digested the fastest. If you take the oxy on a stomach full of complex carbohydrates, protein and fat, the time release will work as intended or equally well with an empty stomach. But taken with sugar it is about the same as alcohol and rushes the medicine into rapid breakdown and into the bloodstream along with the sugar. If you chew the Oxycodone and then consume sugar or if you are taking the instant release form, you will get a terrible rush that will leave you like a zombie in less than 20 minutes. The sleepiness is from the codeine that is also added to the Oxycodone. I strictly take IRs and use less medication than ever before and I know longer feel drowsy especially in the evenings. I always used to go off to that oxy codeine doze when I took the Oxycodone, especially around 6 or 7 p.m. and wake up about 10 or so and couldn't go back to sleep the rest of the night until about 3 or 4 in the morning. I hate the effect of the codeine but it enhances the effects of the oxy. Taking straight Oxycontin requires a lot of discipline not only with the amount but also with diet, exercise etc. I don't doze off and I feel great and have a lot more energy.

But the reason I take the instant release is a bit more complicated and it's really important to understand the dynamics of this medicine. I've done a lot of research on this medicine and other areas. I'll put this in layman's terms as much as possible. You are most likely taking the generic version of oxy. There's a substantial difference between generic medications and the originals. Generic manufacturers are allowed to use 80% to 103% of the actual medicine. So guess which level they're going to go after? Then there are the fillers which are going to be the most inexpensive lots of garbage they can acquire especially since today most come from China. It then becomes seriously questionable what is even in any generic medication especially if it came from China complete. Your doctor or pharmacist will never have a clue what level of medicine is in the pill and least of all know what fillers are being used. Plus pharmacies are constantly changing their generics to, you guessed it, the cheapest flavor of the month. Add to this each person is different in their digestion and absorption and metabolic and absorption rates. For example I am totally lactose intolerant. Consider each tablet has to be exactly the same size, compressed and a coating added so it isn't broken down in the stomach. The fillers they use to make up the difference in space many times are lactose. My body can't break down lactose so that pill leaves my body just as it entered. So for a lot of years I went into withdraw not understanding what was happening. And my back pain became more severe as to make me unable to walk. Amazingly there has been no research performed on the effective intake for totally lactose intolerant patients. Yet many people lose their ability to produce the enzyme that breaks down lactose as they become older. Plus many other ethnic groups are largely lactose intolerant. We're the only country in the world that regularly consumes milk after the age of 7 thanks to heavy lobbying by the dairy industry. After doing more research I found out that how much prescribed medicine actually gets into your bloodstream is a Big Fat Guess at best. Take into account the differences of each individual and it's so many variables involved there's no question why it is known today over 1,000,000 deaths occur annually due to problems associated with medicines.

I take the capsule form and not the pill form of oxy where the lactose fillers are loose and not compressed into the medicine. 

Now if you've only been taking the oxy for a couple years or less you will definitely get this kind of rush. I never used to like chocolate or candies and other sweets but oxy gets people hooked on these things subconsciously as your brain tries to continually get that rush. I experienced this same thing many years ago. Today I've been on Oxycontin in some form or another for almost 10 years and quite honestly don't consciously feel anything until I forget to take it for about 24 hours and my back muscles lock up in unbelievable pain. Those days of getting any kind of rush are long gone. 



Pete trips again!
Veteran Member

Date Joined Nov 2006
Total Posts : 1899
   Posted 1/21/2008 3:52 PM (GMT -6)   


What you say is most interesting Doing much better, I have often heard that generics were not nearly as good as the real thing and have felt that way myself for years but I've never heard it as bad as you make it out to be. I to have been taking oxy in one form or another for a long time probably over 20 years. I also do not feel any buzz or dopy feeling when I take it along w/ my methadone. I do get tired and drink a lot of coffee to stay alert at work. I have noticed that my meds work faster w/ coffee an the pain decreases quicker w/ cafine. Kind of the Excedrine effect. Coffee also does not keep me awake the way it used to, I'm sure I don't get quality sleep after drinking alot of it. Good luck everyone in releiving your pain!

Your friend,


54 years old, Surgury, Radical Prostatectomy 8/20/03, PSA 6.6, Gleason 3 + 3 = 6, Adenocarcinoma extent (moderate) Stage & Margin:T2NOMX, No Metastases, Organ Confined, bone scan: Neg. Testosterone Theropy since 12/06. I am's what I am and that's all that I am!!! 

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