It looks as if you have done your part in research and hopefully this Endo Doc will do his part.
Have you tried doing a search on Adrenal and pit.gland diseases and see what pops? Maybe this is something genetic and that is also a place to reserve looking if the Endo doesnt find answers for you.
Now here I am going to say something and even though there has been numerous case studies as well as research in tis not one thing has actually shown a positive direct cause.
I am 51 as of last week and suffered extreme migraines for the better part of my life with times in there that they were far worse and more occurring in frequency then others,i.e. during pregnancy,menstrual cycles,and some that we cant make a link to. Like you I went thru H*LL! Years of Docs, specialists,ERs, and once maybe twice a direct link between my headaches and placenta abruption resulting in the premature birth of two children and subsequent loss of one due to that prematurity.
I spent 75 percent of each pregnancy in the hospital where they could control the pain and vomiting that was never ending during certain trimesters.
Then after the last birth at 41 I had a partial hysterectomy and was started on hormone therapy and Walla! the headaches ceased to exist altogether. Just like that not another headache that I had to take more then my usual meds for,not one ER visit nothing. For the first several years I lived in constant fear that I was going to do something to make them recur but they didnt.
At one time I was taken off HRT since they thought I had been on it too long with the risk of cervical cancer being greater in women over 50 on hrt therapy and guess what happened? You got it! They came back with a vengence.
Needless to say even today postmenapausal I am still on the prempro and will remain on it regardless of the the increased risks and yes I had to sign a waiver stating I knew the risks but anything is better then the constant headaches.
I did find one headache specialist in Ohio that said he was a firm believer in hormone imbalances in relation to migraines.
I dont have any idea if I had more or less or not enough of one thing or another as we never went so far as doing al the testing and seeing a Endo and frankly I could care less as long as they dont come back in this lifetime.
During pregnancy when the hormone levels were changing so much and so often this is when my headaches were at their worst. During certain days of the menstrual cycle the same thing.
So what your saying here makes perfect sense to me and dont stop charging on as there is relief possible if you can find someone that believes in this hormone relationship with migraines and you are willing to forego the treatment as hormone therapy for a man not going thru menopause is probably going to cause some problems.
So if the endo doesnt find answers by way of Pit ot Adrenal gland issues other then they are also directly related to hormone levels as well,then there is still hope in the way of HRT therapy.
By the way every symptom you described is exactly as I had them. It was like a constant exxagerated state of PMS or menopause all the time. The hot flashes,the feelings of depression and being in a slump that was never ending,the general feelings of malaise and not being well or healthy,morbid thoughts, stomach pains at times that were not explainable and feeling weak and faint. I spent day after day even without being in a full blown migraine wasting away ont eh couch if I could pull myself there from the bed. I on an average changed my sheets and clothes twice a night if the temps in my room grew to more then 65. I ran a room air conditioner all year round and didnt own a coat for many a winters,never needed it.
Sadly I have one daughter that is 34 and seems to be on the same path as I. I am hoping that we are wrong but at her age and her number of headaches I am seeing some of the same symptoms that I had. I didnt get really bad until I reached 35 with this and then from that premenapausal age until I went on the HRT at about
41 it all got worse.
I apologize for this being so long but I wanted to give you my experience with this so maybe if they dont look hard enough at those hormone levels or dont take them seriously enough you can at least search in that direction for answers or treatment options.
I wish you the best of luck and I want to add here that I had a very difficult time finding any Doc or even person in any field that believed or looked seriously at the magnitude of my symptoms, I suppose they thought it was a blown out of proportion but believe me it wasnt!
Bilateral knee replacements,spondylosis of L-3,4,5 and S-1, osteoarthritis,premenopausal migraines.
Meds: Methadone,xanax,zanaflex,maxide,prempro,K+,indocin,lexapro,neurontin(coming off) lyrica(going onto)