Lucia, I have quite a bit of experience with Actiq. Like any opiate, it really takes a little bit of trial and error before you know if it really will benefit you. I took them for a year and a half, and they were very, very effective at killing my breakthrough pain. However, I will warn you, should this medicine be prescribed to you: IT is prohibitively expensive for 99% of people. Most insurance companies will not pay for the medication because a months supply can cost well over $10,000, depending on dose and quantity. Most insurance companies also will not pay for the medication unless you are diagnosed with a malignant cancer. It is most likely that your doctor will want to go with the more recent version of breakthrough fentanyl, known as Fentora. Instead of a lollipop, it is a little pill-like tablet that you let rest on your tongue. It absorbs quickly through the tissue on the inside of your mouth, and from my experience, it only takes minutes for it to work. So, before you ask for Actiq by name, check with your insurance policy. Also, both the regular and sugar free formulations of the lollipop have been tied to extreme dental decay of molar teeth, mainly because the lollipop, if used as indicated, rests between the upper gum and the molar itself. Both can be an excellent breakthrough pain med, especially if you are prescribed an opiate which tends to block mu and kappa opiate receptors, like methadone. Because Fentanyl is the most potent opiate that humans can be prescribed, I would think about this a little before you ask for it. Besides, I can think of atleast one or two other breakthrough options that you haven't tried, but that is for your doctor to decide with you.