My doctor told me that grapefruit juice is a potentiater for opiate medications and asked me to avoid it, because he said it would make it more difficult to determine the dosing of my medication. I hate grapefruit juice, so I didn't mind. I was curious why it would be a problem, so I looked up "potentiater" to find out. I wouldn't recommend doing that, because it takes you to some very legally questionable websites!
But, here's the most reasonable definition I found, which I've copied from the "Intractable Pain Survival Guide":
"The term 'potentiator' is one used by physicians and pharmacists to indicate that one medical agent makes another more 'potent.' Here, we are talking about agents that make opioids act stronger and last longer."
With that said, I'm not sure I buy the concept at all. I know grapefruit has certain benefits as far as enzymes, but I suspect if you eat a healthy, balanced diet based on your caloric requirements and were to drink a 8 ounces of water 30 minutes prior to your meal, you'd also lose 4 pounds per month. It makes sense that any other low/no calorie substance would take up space in your stomach and cause you to become full faster, thus reducing your intake at mealtime.
The very best weight loss plan I've ever used was a balanced diet, through a fairly well known online program. (I don't want to post the name, because I don't want it to appear as advertising.) When I set up my account, I "checked" that I wanted to lose weight, classfied myself as sedentary, (sit a lot/no exercise plan/activity usually limited to household chores/projects), and set my preferences to avoid fish, soy, egg substitute, and tofu because I refuse to eat any of those things. It returned a 1600 calorie food plan based on the good ol' food pyramid, a detailed shopping list, and a printable menu with the meals, recipes, and preparation instructions outlined. It gave me 3 meals and 2 snacks each day. I elected to use "convenience" foods for breakfast, lunch, and snacks because I was working and needed fast and easy; then I'd do a recipe-based meal at dinner, which usually took about 30 minutes to prepare, from start to finish.
I stayed on that plan for 6 months before my fusion surgery and lost 71 pounds. My doctor said the rate at which I was losing the weight was acceptable and that healthy weight loss is generally 1-3 pounds per week. That was just a result of healthier eating, for me. I've always been lousy at exercising and I didn't have a revelation to go along with my healthy eating; I was just as lazy as always.
I also wasn't able to eliminate the 20-ounce Mountain Dew at breakfast, which I have required to wake up since I was about
8 years old. Some things are just too much to ask!
I've "fallen off the wagon" right now, so to speak, and have gained a terrible amount of weight back. After my fusion, the pain completely took over and I became extremely depressed, so I went back to the fast food, comfort food, and feeding those infernal cravings that crop up as a direct result of evil TV commericals showing gooey, stretchy cheese on a fully loaded pizza or chili squeezing out of that huge hamburger.
That was probably more than the topic really required, but I'm up and hurting so I slipped into babbling. I'll stop babbling now, but it seems a shame to waste what I've written, so I've decided to hit post anyway.