Grapefruit & Water

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Pamela Neckpain
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Date Joined May 2008
Total Posts : 1821
   Posted 8/23/2008 6:09 PM (GMT -6)   
My husband read in a magazine called Health that 1/2 a grapfruit before meals
will cut your appetite down so that you lose 4 pounds a month.
I believe I have read that grapefruit shouldn't be combined with
many medications. Any grapefruit experts on board?

Every time I read something I hear differing opions on water from different
medical experts. Some say you need a lot of water. Some say you should
go by your thirst. Any H2o experts on board.

I like the Forum because it's all of our reading and life experiences put together.

Pamela Neckpain

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Date Joined Dec 2007
Total Posts : 2113
   Posted 8/23/2008 7:06 PM (GMT -6)   
I just started taking biaxin-there is a grapefruit warning in the patient info-it is concidered a major interaction.
There are other meds it interacts with as well but I don't know them all.

Regular Member

Date Joined Jul 2008
Total Posts : 75
   Posted 8/23/2008 8:11 PM (GMT -6)   
The news had a clip on grapefruit and other juices affecting medications, just this week. They did not go into too much detail other than to
say that it is being researched.
They did advise taking all meds with water only. But did not say don't drink the juice later on , which did not make a bit of sense.

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Date Joined Jul 2008
Total Posts : 2317
   Posted 8/23/2008 8:28 PM (GMT -6)   
Hi Pamela.

Not sure exactly which meds interact with grapefruit, but I know I've seen warning labels on some of my prescription bottles in the past. Probably best thing to do is ask your pharmacist. I do have some friends who've done the grapefruit diet. They did lose quite a bit of weight, but eventually stopped eating the grapefruit once they hit their target weight & then put it all back on plus more. Probably the best thing to do is find a diet/exercise program that you can stick with long term. I don't know.

As far as the water, I have the opposite prob right now -- trying to gain weight. I know, I know "a lot of people would die to have that problem" but I think the people who say that have never had to be given IV nutrition. Needles are evil & the nurses sometimes make me feel like I'm somehow trying to make myself sick and not eat. Only the nice ones let my mom smuggle the good food into me, the rest of them shove that greyish slop in front of me & then wonder why I pick at it for over an hour before I can finally gag it all down. :| grr.

Anyways, my PCP said that drinking water at least 30 minutes before meal times helps decrease appetite (I now wait to drink until after I eat). I have been able to gain a pound or so since I changed that habit 2-3 weeks ago. I've been able to eat a lot more food, so maybe there's something to the idea. One other thing I know some people have tried for losing weight is eating soup before a meal. I've heard creamy soup works best because it fills you up more, but I'd think just about anything would work. Make sure it's one of those reduced fat, lower calorie soups or else there's no point (a co-worker of mine learned that the hard way).

Good luck on your diet! Maybe you could send the pounds you're losing over to me? Just a thought. ;)


Regular Member

Date Joined Jul 2008
Total Posts : 191
   Posted 8/23/2008 11:45 PM (GMT -6)   
Hello Pamela, dont know about the grapefriut thing with meds, but if you are trying to loose weight they just came out with a study that showed that low carb diets are the best and the healtiest as well... they act. lower blood pressure. These are the diets they use with alot of diabetics.  I know alot of people have had great results with them. Wishing you well as always!!

Regular Member

Date Joined Jul 2008
Total Posts : 243
   Posted 8/24/2008 4:42 AM (GMT -6)   
My doctor told me that grapefruit juice is a potentiater for opiate medications and asked me to avoid it, because he said it would make it more difficult to determine the dosing of my medication.  I hate grapefruit juice, so I didn't mind.  I was curious why it would be a problem, so I looked up "potentiater" to find out.  I wouldn't recommend doing that, because it takes you to some very legally questionable websites!  shocked  But, here's the most reasonable definition I found, which I've copied from the "Intractable Pain Survival Guide":
"The term 'potentiator' is one used by physicians and pharmacists to indicate that one medical agent makes another more 'potent.' Here, we are talking about agents that make opioids act stronger and last longer."
With that said, I'm not sure I buy the concept at all.  I know grapefruit has certain benefits as far as enzymes, but I suspect if you eat a healthy, balanced diet based on your caloric requirements and were to drink a 8 ounces of water 30 minutes prior to your meal, you'd also lose 4 pounds per month.  It makes sense that any other low/no calorie substance would take up space in your stomach and cause you to become full faster, thus reducing your intake at mealtime.
The very best weight loss plan I've ever used was a balanced diet, through a fairly well known online program. (I don't want to post the name, because I don't want it to appear as advertising.)   When I set up my account, I "checked" that I wanted to lose weight, classfied myself as sedentary, (sit a lot/no exercise plan/activity usually limited to household chores/projects), and set my preferences to avoid fish, soy, egg substitute, and tofu because I refuse to eat any of those things.  It returned a 1600 calorie food plan based on the good ol' food pyramid, a detailed shopping list, and a printable menu with the meals, recipes, and preparation instructions outlined.  It gave me 3 meals and 2 snacks each day.  I elected to use "convenience" foods for breakfast, lunch, and snacks because I was working and needed fast and easy; then I'd do a recipe-based meal at dinner, which usually took about 30 minutes to prepare, from start to finish.
I stayed on that plan for 6 months before my fusion surgery and lost 71 pounds.  My doctor said the rate at which I was losing the weight was acceptable and that healthy weight loss is generally 1-3 pounds per week. That was just a result of healthier eating, for me.  I've always been lousy at exercising and I didn't have a revelation to go along with my healthy eating; I was just as lazy as always.  redface   I also wasn't able to eliminate the 20-ounce Mountain Dew at breakfast, which I have required to wake up since I was about 8 years old. Some things are just too much to ask!  tongue   
I've "fallen off the wagon" right now, so to speak, and have gained a terrible amount of weight back.  After my fusion, the pain completely took over and I became extremely depressed, so I went back to the fast food, comfort food, and feeding those infernal cravings that crop up as a direct result of evil TV commericals showing gooey, stretchy cheese on a fully loaded pizza or chili squeezing out of that huge hamburger.    smhair
That was probably more than the topic really required, but I'm up and hurting so I slipped into babbling.  I'll stop babbling now, but it seems a shame to waste what I've written, so I've decided to hit post anyway. wink

Post Edited (BionicWoman) : 8/24/2008 3:46:09 AM (GMT-6)

Veteran Member

Date Joined Aug 2006
Total Posts : 9664
   Posted 8/24/2008 3:51 PM (GMT -6)   
This is a good topic ty for bringing it up yeah
Antibotics are reduced in effectiveness when taken with oranges. not sure about the grapefruit interactions.
But grapefruit juice does interact with depression medications such as Nortriptyline, I'm just unclear as to how it interacts with it.
You might be able to ask your pharmacist why the medication is not supposed to be taken with grapefruit. Just a suggestion..
Take care and hope you have a painfree day soon! soft hugz till then.........
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Pamela Neckpain
Veteran Member

Date Joined May 2008
Total Posts : 1821
   Posted 8/24/2008 7:15 PM (GMT -6)   
Hmmmmm. Oh, me oh my! I certainly wouldn't want to potentiate my opiates with
grapefruit juice.
Thank you for that information. : )
I'm going to have to buy that book by the name of "Intractible Pain Surivival
Guide." Where do I get it? I think you can post it outloud. If not, e-mail me please.
It sounds like a book we'd all benefit from.
Mt. Dew. Eh? Does it potentiate anything? Coffee "potentiates" my brain in the
morning. Without coffee, my brain is a clump of wet mop.
Pamela Neckpain
Funny thing: Someone left three large grapefruits in a plastic bag right by my
front door. No name. Anyway, I got kinda Paranoid about those grapefruits.
(It was BEFORE I'd read the 'potentiate' thang) There's this strange woman
in our apartment complex who seems to not like me because I don't like her.
I got to suspecting that she might have used a hypodermic needle to poison
those now-scary looking fruit. I tossed them. Pity?

Pamela Neckpain
Veteran Member

Date Joined May 2008
Total Posts : 1821
   Posted 8/24/2008 7:36 PM (GMT -6)   
sjkly:It sounds like grapefruit is just not a good thing when taking medication.
tiggers:The reporter needs lessons?
Frances: Water and soup for me before meals. What are they feeding you? What treats does Mom bring?
Ladyred: I might never go potty again if I went on a low-carb diet.
Chartreux: I always have oranges. Maybe that's why my antibiotics don't work so good.

We can learn a great deal from each other. Much like dogs learn a lot from cats. : ) Of course, none of us
claim to be pharmacists or doctors but we try. We read. And ALL of us are strongly motivated to help ourselves
and each other.
Pamela Neckpain

Regular Member

Date Joined Jul 2008
Total Posts : 243
   Posted 8/24/2008 10:59 PM (GMT -6)   
Pamela, you don't have to buy it.  It's online:
There's a lot of good information, on a variety of topics. 
Ironically, caffeine is listed as a potentiater as well, but I just have to risk it with the morning Dew, in exchange for potentiating my conciousness!  tongue tongue

Pamela Neckpain
Veteran Member

Date Joined May 2008
Total Posts : 1821
   Posted 8/25/2008 12:04 AM (GMT -6)   
Coffee! Well, I could have guessed as much.
I have Attention Deficit Disorder. When my pain
started 6-7 years ago, I gave up the medication
to help me with this terrible condition. Now, I'm
wondering if it might help. My psychiatrist wants
me to give it a try. Hmmmmm?
I'll be ordering the book if it's not too $$.
Pamela turn

Post Edited (Pamela Neckpain) : 8/24/2008 11:08:16 PM (GMT-6)

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