I have been taking pain meds for a few years, and I have had my share of side effects from them. I recently changed from Morphine to Methadone as my primary pain medication. The outcome of the change has been mixed and I will give it some time to adjust. One thing I have noticed and it has become a problem is that my short term memory has been effected. I am not sure if it because I am getting older or is it the Methadone? I have noticed that as a thought comes into my mind, it does not stay there, for an example is that I am going downstairs for something and in route I forget why I am going. Things like this seem to increased when I started the Methadone, I have asked my Dr. but he felt that there was no connection with memory and Methadone. any thoughts?