That huge jump was just an example, no, 10mg does not last 12 hours. I think being the nature of the consistency of the pill, alot of goes thru the system un used. I took a 10 mg and put in my gum/cheek last nite to see what the breakdown time was from saliva/moisture, the majority of the pill was still there after two hours and was hard. Now, everyones system being different. Im sure that i pass more of the pill than my body absorbs. Now at that rate, thats some expensive #@#%
. So with the possible increase to 40, and instant release oxycodones, i might possibly get some relief, otherwise to get any relief i double up on the 10/325 twice a day and have some decent pain relief, still there but not as intense. Lately, my rib cage hurts, from holding my breath, anticipating the next wave of excruciating jabs of pain in the buttox and calf of my leg, like being stabbed with huge knitting needles. Just looking for somthing that works, im sure PMD will come up with a plan, thats his job and he is good at it. He is my neigbor, my friend and most of all, he is my doctor who cares.