yes, i have taken percocet 10/650 for years every four to six hours for fibromyalgia pain and it works great for me most of the time about a year ago I started having problems with it not working so they tried me on some other pain meds. That was no good. After about three months I went back on the percocet and it worked again like a charm
Now there are days when the percocet and the lyrica I take just don't cover it and I add an antiinflammatory and that seems to help me.
Try it and see if it works for you.