Posted 4/15/2009 9:51 AM (GMT -6)
In my very humble Opinion, ANY long acting med provides longer, stronger, smoother and altogether better QUALITY Pain Relief than ANY SHORT-TERM medication, regardless of the neat little buzz the ST's may offer!!!
It would be "odd" for your Doc to pop you on LONG ACTING meds for a couple to several days, then switch you BACK to highly addictive short-acting meds. Weird.
I have taken MSContin ER 3x a day, at varying doses (right now 7am=60mg; 3pm=30mg; & 9pm=30mg), for 4.5 years. I also use Morphine Sulfate IR (60mg per day) for break through pain. MSContin ER is the Generic for Oramorph, Kadian & a couple of other name brands.
Opana is otherwise known as Oxymorphone.
i tried to find out "What is the difference between Oxymorphone (Opana) & Oramorph?" This is all I found, a quote from a large Medicaid Study:
"Dr. Correia noted that oxymorphone has been historically associated with relatively higher incidences of constipation, respiratory depression, emesis, and physical dependence than other drugs in this class. He also noted comparative metabolism with other drugs in this class with regard to drug interactions. He stated there is no new clinical evidence to indicate any of these drugs offers an overall advantage." The Medicaid Pharmacy & Therapeutics Committee met on Friday, May 9th, 2007 from 8:00 a.m. to 4:00 p.m. in Meeting Room 6, Concourse, Empire State Plaza, Albany, New York.
Disappointingly & predictably, the studies final recommendations of "what drugs to pay for" had only to do with budgetary concerns and represented and otherwise senseless mismash of Oramorph & Oxymorphone Products. Recommended (Preferred Drug): Duragesic (fentanyl), fentanyl patch, Kadian (morphine sulfate SR), morphine sulfate SR, Oramorph SR (morphine sulfate SR); NonPreferred: Avinza (morphine sulfate ER), MS Contin (morphine sulfate CR), Opana ER (oxymorphone ER), oxycodone CR, Oxycontin (oxycodone HCL CR).
Supposedly this was "okay" because "all of the medications performed equally well" (ACCORDING TO WHOM???). Actually, I believe THESE folks (The Medicaid Pharmacy & Therapeutics Committee) CHOSE to believe this was so because it was projected that controlling the utilization of medication in this manner would save the State of NY $114 million in 2008!!!
Anyway... "Morphine and codeine are the 2 naturally occurring opiates, while hydromorphone, oxycodone, and hydrocodone are semisynthetic. Meperidine, fentanyl, methadone, and propoxyphene are synthetic opioids." (Medscape) I just thought that was kind of interesting.
All that was explained for a difference in the "performance" of the individual drugs is that it represents a "perception" on the part of consumers. We all have slightly different Central Nervous Systoms, amounts of various neurotransmitters & pain tolerances. The drugs "may" metabolish differently or be physically processed variably among the population. Also certain people will be allergic to something in the "making" of one drug, and not another!
Sorry so long!!!
"When I stand before thee at the day's end, thou shalt see my scars and know that I had my wounds and also my healing"~Rabindranath Tagore
DISORDERS: Osteoarthritis; Degenerative Disc Disease (degeneration at C- 2 to 4 with Osteophytes, T- 8 to 12; L-4 &L-5); Facet Joint Disease through out; Spinal Stenosis; Neurogenic Claudication; Anterior Displacement at the L-4/L-5 site; De Quervain's tenosynovitis of the wrist; Ulcerative Colitis; Diverticulitis; Chronic Clostridium Difficile; Irritable Bowel Syndrome
TREATMENTS: 3 Radiofrequency denervations (Thoracic/Lumbar Facet Joint Nerves); 2 Epidurals (Cervical Herniations, Cervical Facet Joints)
MEDICATIONS: MSContin ER 60mg/30mg/30mg ; Morphine Sulfate IR 15mg 2x prn; Naproxen 500mg 3x; Tizanadine 2mg 1- 3 at bedtime, 1- 2 2x daily; Clonazepam 1mg; Wellbutrin 400mg; Lexapro 30mg; Topomax 100mg; Provigil 200mg, 2x; Metoclopramide 20mg, 2x; Asacol 800mg, 3x, Prevacid ? 2x