A great site for pump information is a yahoo groups called Pumpsters. It is designed for individuals either considering pumps or that already have pumps. There is a wealth of information within that group.
Question? Are you adding Prialt as a new drug to your mixture or have you had it on board for some time? Some people have good experiences with it - I and many people I have talked with have had very negative side effects. Within one week I started having psychotic thoughts and increased pain. The psychosis is a big problem with this medication. For me, I thought I was being poisoned and kept having thoughts that I needed to "cut my pump out" to stop the medication. That is one drug I would do a lot of research on before I put it in my pump. My experience with Prialt was a complete nightmare. A very good friend of mine ended up in the psychiatric unit after coming in through ER. She was having so many psychotic events she had to be sedated until the medication was removed and the remaining amount worked it's way out of her system. Log on to Pumpsters, they have quite a few files about Prialt and the group is large in numbers so they can give you a wide variety of experiences. Last thing - you are swapping out some heavy duty narcotics for Prialt. It is a non-opiate and the the clinical data it not the strong on it as a sole pain med and I know you have to be very careful with what other meds you mix with it.
Here is the Warning Section for Prialt's Package insert:
Severe psychiatric symptoms and neurological impairment may occur during treatment with PRIALT. Patients with a pre-existing history of psychosis should not be treated with PRIALT. All patients should be monitored frequently for evidence of cognitive impairment, hallucinations, or changes in mood or consciousness. PRIALT therapy can be interrupted or discontinued abruptly without evidence of withdrawal effects in the event of serious neurological or psychiatric signs or symptoms.
Patients should be cautioned against engaging in hazardous activity requiring complete mental alertness or motor coordination such as operating machinery or driving a motor vehicle during treatment with PRIALT. Patients should also be cautioned about possible combined effects with other CNS-depressant drugs. Dosage adjustments may be necessary when PRIALT is administered with such agents because of the potentially additive effects.
Withdrawal From Opiates
PRIALT is not an opiate and cannot prevent or relieve the symptoms associated with the withdrawal of opiates. To avoid withdrawal syndrome when opiate withdrawal is necessary, patients must NOT be abruptly withdrawn from opiates. For patients being withdrawn from IT opiates, the IT opiate infusion should be gradually tapered over a few weeks and replaced with a pharmacologically equivalent dose of oral opiates. PRIALT does not interact with opiate receptors and does not potentiate opiate-induced respiratory depression
Full information can be found here:
Good luck with the Prialt - please ask you doctor so detailed questions about his experiences with it. Let me know if I can be of any other help.
Co-Forum Moderator for Chronic Pain
Rare neurodegenerative /movement disorder called “Multiple System Atrophy”. Mobility issues,, neuropathic pain, spasticity, central apnea, collagenous colitis, pain, swallowing and respitory involvement, Implants: intrathecal pump & neurostimulator. Extra features: O2 & wheelchair
Post Edited (Stella Marie) : 7/29/2009 4:46:10 AM (GMT-6)