New Dosing of Ultram

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New Member

Date Joined Aug 2010
Total Posts : 4
   Posted 8/24/2010 2:19 PM (GMT -7)   
 First I want to thank everyone for the great advice and support you all have provided 
me in this forum. It was really appreciated. Well, today  I had the 3rd set of cervical epidural injections.  Im pretty sure he gave me more than this last 2 times. Simply because I heard him say "Shoot here" alot more times than before.
  After he was done I discussed the fact that Ultram wasnt doing so well to relieve
the pain. He told me to start taking 2 50mg 3 times a day. Ask me was I taking muscle
relaxers, but when I told him no he didnt offer any. I will go back for a follow up in
2 weeks.
  Now Im just worried right now about taking 2 at a time. I hate not knowing what
this will do to me. I have to be alert when I am working as I deal with alot of money
during the day. There is no room for error.
    I would appreciate anyones experience with taking Ultram at the dosage Im satarting this evening. Thanks again You all are great!

Regular Member

Date Joined Jul 2010
Total Posts : 416
   Posted 8/24/2010 2:29 PM (GMT -7)   
Ok, I am not a dr. I just want to start by saying that. I too work with money, kids, and drive quite a way for work. I also have 5 kids at home and a hubby that is gone til the weekend, due to work. I take 2 Tramadol at a time and it doesn't, nor has it affected me. Everyone is different though. You might try it on the weekend to see how your body reacts to it. Next time you go in mention how he talked about muscle relaxers and ask him if he still thinks it might be something that can help you. I find that they get distracted and don't always remember unless you remind them Good luck and hope you feel better. Heather
Big Hugs, Mama6

DX. with Fibromyalgia, Narcolepsy, Poss. RA or Psoratic Arthritis, Herniated disc 3x in last 7 months
Meds: Nuvigl, Cymbalta, Tramadol

Mother to 5 wonderfull kids. Oldest is 18 and just left the nest for animation school. Youngest just started 2nd grade. So I am crazy, and feeling my age plus some.

Veteran Member

Date Joined Oct 2009
Total Posts : 4906
   Posted 8/24/2010 4:22 PM (GMT -7)   
Good thing he didn't give you a muscle relaxant because several of them, taken with Ultram, will give you serotonin syndrome. about the only muscle relaxant that is ok is Valium (diazepam). Yes, at higher doses it's called a tranquilizer. Even 1 mg (half the smallest dose) works well for me. I take it at bedtime. It's also used for stopping serotonin syndrome because it hits the same receptors.

Tramadol also comes in Extended Release. I'm starting to have pretty good luck with that at night. The instant release seems to only work about 4 hours, so it doesn't get me through the night. I thought I was having headaches with the ER, but I think it was other stuff I took at the same time.

Veteran Member

Date Joined Jul 2008
Total Posts : 2315
   Posted 8/24/2010 4:47 PM (GMT -7)   
You can always try taking 2 when you first get home from work & see how you feel. If you're really tired, you know to wait until the weekend to try it again. Otherwise you can take a double-dose tomorrow morning.

In my experience, it's not terribly strong so 2 probably won't knock you out, but try it at night if you're really worried.

feel better,

Veteran Member

Date Joined Apr 2008
Total Posts : 1522
   Posted 8/24/2010 5:07 PM (GMT -7)   
I've been taking tramadol for about 2 1/2 years and I get a bit loopy when I take two at a time. That dose also makes me rather sleepy after about 3 hours.

I take 1 1/2 at a time when I have a lot of pain. It's enough to help but it doesn't make me talk non-stop.

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 8/24/2010 5:28 PM (GMT -7)   
If I take two (one at a time) tramadol four hours apart before bed I feel drugged and have a hard time concentrating the whole next day.

Regular Member

Date Joined Aug 2010
Total Posts : 215
   Posted 8/25/2010 3:37 AM (GMT -7)   
tramadol is one of those medications you can feel even taking 1/2 of a 50 mg pill because of its SE inhibition effects. For me I personally didn't like the way it made me feel, but for certain types of pain it worked very well (dental pain) and other types it worked like a baby asprin (lower back).

I would try take 1 1/2 tablets first and see how you feel on that as sometimes even just a 1/2 dose can make a difference. you can use this to titrate yourself up to 2 pills per dose as an in between step. At higher doses the opoid activity is more noticable at about the 90 minute mark, so you might not want to drive until about 2 hours after you have taken it to see how it will effect you (remember the relief SHOULD last 6 to 8 hours).

I prefer Nucynta, as it doesn't have the strong SE zombie properties that tramadol has, though it still feels like taking an anti depressant. However its a schedule 2, but most doctors are more willing to prescribe it vs other schedule 2s due to its lower risk of dependency.
MRI revealed a bulging disc w/gel lost at L5 and showed the bulge touching nerves, causing sciatica. Diagnosed w/ Arthritis which is responsible for joint inflamation pain. Treatment: Nucynta 50-100 mgs every 6 hours (schedule II narcotic, moderate MOR receptor activity and moderately strong NE reuptake inhibition), Celebrex 100 mgs, Epidurals, Radio Freq nuerotomy (sept 8th, 2010)

New Member

Date Joined Aug 2010
Total Posts : 4
   Posted 8/25/2010 4:26 AM (GMT -7)   
Ok I appreciate the feedback. Suppose I took 1 about every 2 hrs for a total of the prescribed 6 every day. I did take 2 laft evening and it didnt really seem to effect me as far as drowsiness goes. I work all day today so I am trying to decide how Im going to do this. The last dose will be taken when I get home from work.

New Member

Date Joined Aug 2010
Total Posts : 2
   Posted 8/25/2010 6:00 PM (GMT -7)   
Does ultram really work for you. Its really a very bad drug. Even my pain doc explained this to me. The more ultram you take the higher the risk of seizures. And I'm talking serious seizures. It also has nasty side affects. If it works for you that's great. Just be careful. Also I really hate when doctors prescribe and prescribe this med because they are afraid of opioid meds. Its just ignorance. opiate meds are actually one of the safest class of meds there is. There is no upper amount to where they become unsafe. Its actually one of the few meds that you can take very high doses and be safe. Where as taking too much tylenol can ruin your liver, ibuprofin kills your stomach like most nsaids etc. I think a lot of dr's need to learn the difference between addiction and physical dependency. Luckily I have a very good pain doc who always seeks my input. He let's ME suggest different meds I've heard of then we weigh the benefits and negatives and we decide what's best for me together. Any questions e mail me at

Mrs. Dani
Veteran Member

Date Joined Jun 2009
Total Posts : 2787
   Posted 8/25/2010 8:43 PM (GMT -7)   


   Dear Davis,

     I would encourage you to read our CP101 to fully understand all methods used for pain management and "why" such methods are used with particular types of pain / patients. Help to learn a bit about risks and benefits associated with all treatment options as well.~~>

     This link is very helpful to new commers also :-)  

     I would like to encourage you to start your own introduction so that we can welcome you to the community properly!

     Thank you for your time,

TWO roads diverged in a yellow wood
And sorry I could not travel both
And be one traveler, long I stood
Chronic Pain Moderator

spinal soldier
Veteran Member

Date Joined Dec 2009
Total Posts : 687
   Posted 8/26/2010 8:35 PM (GMT 0)   
hello mom at work, flexiril [cyclobenziprine] is the only muscle-relaxant that could interact with tramadol to cause seretonin syndrome, it is a similar drug to the tricyclc-anti-depressants such as amitriptyine or imipramine which have a seretonin effect. davisgwar is right about why doctors seem to want to perscribe ultram because they are afraid of the other opiates but in so doing they open people up to danger with the combination of drugs like cymbalta, any SSRI or savella or flexiril because they directly interact. i find that for your reason of having to keep your wakefullness up hydrocodone meds are good for that but every one is different. provigil or amphetamines are used by some PM docs when a patient needs high doses of potent opiates to control their pain and still have alertness.
L4,L5,S1 bilateral Laminectomies, Foraminotomies 2002
L4-S1 PLIF with instumentation 2008

current Rx: MScontin 100mgs 2x, dilaudid 8mgs 4x p.r.n., soma 3x, vistaril 25mg 3x prn, wellbutrin 150mg 2x(ADHD),Adderall 20mgs 2x(ADHD)

Mrs. Dani
Veteran Member

Date Joined Jun 2009
Total Posts : 2787
   Posted 8/27/2010 5:42 PM (GMT -7)   
  Many medicines have the "possibility" to interact with Tramadol. For accurate information reguarding possible risks speak with your Pharmacist and Doctor. Also, there is a wealth of information to be found on the internet. Here is a good place to start
  I curently take 3 medications that could "possibly interact" with tramadol. In my case it ment more frequent monitoring for the first month(s)
TWO roads diverged in a yellow wood
And sorry I could not travel both
And be one traveler, long I stood
Chronic Pain Moderator
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