I don't notice a difference, but my pharmacist said to be careful about becoming overheated or running a fever. As in no hot tubs, hot baths, or strenuous activites that would cause a significant rise in body temperature because it could release the medication quickly. Which is what Beckay just said as well. I would call your pharmacist and see if they have any information for you.
The worst sin towards our fellow creatures is not to hate them, but to be indifferent to them. That's the essence of inhumanity. George Bernard Shaw
Pelvic adhesive disease, Irritable bowel syndrome, SI joint pain, 7 pelvic surgeries for pain, ovarian cysts, adhesions, and a kidney stone! Wait, future medial transcriptionist I must say ureteral calculus!