Anyone taking Amrix?

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Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted Yesterday 9:24 PM (GMT -6)   
My doctor gave me Amrix 5 days ago and I'm having a terrible side effect from it- blurred vision. I've gotten used to the drowsiness, but this blurred vision is a pain! mad
I love to read and I'm a teacher so I need sharp vision.
Does the blurred vision go away? Or do I have to live with this aggrevation? shocked
Also do you suffer with very dry mouth? I wake up at night with my mouth feeling like someone stuck a hairdryer inside it. My tongue was stuck to the roof of my mouth! smhair
The doctor mention an alterative to the Amrix. I can't remember the name of it but it started with "sc"? She said it worked only on the pain receptors and some people say it doesn't work for them.

Veteran Member

Date Joined Oct 2009
Total Posts : 5029
   Posted Today 9:06 AM (GMT -6)   
Amrix is just Flexeril, aka cyclybenzaprine. That's the one that gave me serotonin syndrome when I took it 12 hours after tramadol. It was really horrible for dry mouth, nose, eyes. I only took it at night and it put me to sleep 4 hours after taking it. Other side effect I hated was the hangover that lasted 18 hours after I took the med.

Was the other med skelaxin or soma - other muscle relaxers? My pain doc mentioned trying one of those for my fibro and back spasms. I have had good results taking occasional very low dose Valium, which is a very good muscle relaxer at 1 or 2 mg. Zanaflex is another for spasms.

Soma and Zanaflex are addicting. Skelaxin can cause nausea and vomiting - so have antinausea med handy for your new stomach! I have a small bottle of paregoric for serious emergencies, keep a tiny one in my purse. Tastes incredibly awful, but stops vomiting in a couple of seconds. I mention because of your fundo.

Forum Moderator

Date Joined Feb 2003
Total Posts : 16799
   Posted Today 12:35 PM (GMT -6)   
I never have done well on Flexeril and will not take it because of the nasty side effects. I would call the drs office on Monday morning and speak with the nurse and ask that they call you something different in. I did very well on Zanaflex but then you never know if it will work that well for someone else. Take care.


Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted Today 4:50 PM (GMT -6)   
Thanks alcie & susie,
I'll keep it in mind about those medicines. My mother has to take soma for her muscle aches she gets during the night.

Veteran Member

Date Joined Apr 2009
Total Posts : 856
   Posted Today 5:37 PM (GMT -6)   
I've never done well on Flexeril either. It makes me feel so cranky and just all around awful.


Veteran Member

Date Joined Aug 2006
Total Posts : 9664
   Posted Today 10:56 PM (GMT -6)   
write down all the side effects your having and phone your doctor's office first thing Monday
Morning maybe they can get something else for you to try.
Sure hope you can get something that'll help with the least side effect for you...
Hope your doing better soon...
* Asthma, Allergies, Osteoarthritis, Spinal Stenosis, Degenative Disc (Lower Lumbar S1-L3 and Cervical C5,C6, C8 and T1), Fibromyalgia, Gerd,
Enlarged Pituitary Gland, Sjogren's, Ocular Migraines, mild carpel tunnel, ect.... "Would be nice if we could use the edit button in real life"...


Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 9/26/2010 8:53 AM (GMT -6)   
I'm out of amrix samples today. Took the last one last night. The medrol pack runs out today too. She said to start ibuprofen back up today in case I get rebound inflamation from the medrol ending.
It's raining today so I'm achy from the low pressure system. :(
Yesterday I was able to go almost all day without the brace with very little pain. :)

Regular Member

Date Joined Aug 2010
Total Posts : 215
   Posted 9/26/2010 11:14 AM (GMT -6)   

I did not know that zanaflex was addictive, although I was aware that some people felt it increased the anaglesic effects of some pain medications. I prefer not to use it because it makes me feel dizzy, probably because it affects norephedrine production (reduces it by tricking the body) and well my pain medication's (Nucynta) partial mechanism of action is through increasing NE by stopping the reuptake of it or NRI (its a low-moderate stregnth opioid, but a fairly potent NRI and its disassociative side effects at the higher effective doses can have some not so nice side effects, mainly mild halucinations, feeling disconnected with self/others, time perception feels weird and spacing out is common; however at 150mgs the pain relief is OUTSTANDING so sometimes the side effects are worth it. At 50 to 100mgs the side effects rarely appear but pain relief is not always achieved. Nucynta does have some mild direct effect on seratonin levels, and its potent NRI effects can indirectly raise seratonin levels as well, so I honestly think that at 150mgs, I could be experiencing the the pre-stage of seratonin syndrome. The effects raise in curve fasion, not a linear one, so for me 150 mgs has double the effects that 100 mgs seems to have.)

As far as flexiril goes, I genuinely dislike the side effects, but feel the medication is a good muscle relaxer. The super drowsy effect does take a while to set it, but once it does, even 5 mgs can make me pass out for 10 to 12 hours and upon waking it seem to feel sedated and sluggish for about the next hour. After that, my energy levels seem to return to normal though. At 5 mgs, an occasional dose of clobenzaprine taken with 50-100 mgs of nucynta shouldn't be an major issue, but both pose of risk for seratonin syndrome so its best for me to avoid cyclobenzaprine unless im having really bad spasms. I would never take the combination with the 150mg nucynta max dose though, I'd be seeing colors galore :P
MRI revealed a bulging disc w/gel lost at L5 and showed the bulge touching nerves, causing sciatica. Diagnosed w/ Arthritis which is responsible for joint inflamation pain. Treatment: Nucynta 50-150 mgs every 6 hours (schedule II narcotic, Mu Opoid agonist and NE reuptake inhibitor), Celebrex 100 mgs, Klonopin .5, Epidurals, Radio Freq nuerotomy (sept 8th, 2010)

Veteran Member

Date Joined Jan 2010
Total Posts : 3557
   Posted 9/26/2010 6:15 PM (GMT -6)   
Hi couchtater,

I have been using Amrix for the last few months on an 'as needed' basis...

It's hard to say if all the side effects you are experincing are due to this or possibly the Medrol (steroid) pack you are taking..

So..a suggestion would be to wait a week or so after being done with that and then you can see if you are still having issues..

Also..when I first switched over to MSContin (morphine sulfate ER)...I had a lot of side effects that actually took a few months to get over..nausea, fatigue, blurred vision, etc..

I am a big proponent of giving a new medication at least a month (unless having serious allergic reactions that require immediate attention)...Far too many people (not saying you...)...only give medicines a few days..or week and then give up..

I actually really like this new medicine as the 24 hour release really keeps the fatigue level down as opposed to the regular Flexeril tablets...And it does a fantastic job at muscle relaxing:)...

So..I would just speak with your Dr. and keep them posted on the side effects and do as they advise..

Take care,
SB and "the pup who snores loudly" 
ACDF C5-C7, (no hardware), with autograft bone Nov. 2001
(reabsorption of bone 2 years later...still lost in body..expect to burp it out at anytime..haha")) 
ACDF with hardware, allograft bone Nov. 2005 
Anterior and Posterior CDF, allograft bone with BMP, removal of old hardware, use of titanium plates, rods, screws, & kitchen sink (lol) Oct 2006

Veteran Member

Date Joined Oct 2009
Total Posts : 5029
   Posted 9/26/2010 6:41 PM (GMT -6)   
Joy -
Are you doing any PT or exercises on your own? That's the standard Rx for back pain and fibro, at least to start with. I've been working on strengthening my core for a couple of years, in between being too exhausted from rads for breast cancer and then getting over the accident that shoved my stomach into my chest, broke 3 ribs and messed up my knee. The exercises are all pretty much the same for each condition, and they do help. Actually, what I like best is swimming. Before all this started I was doing 20 pool lengths daily, which isn't bad for a senior. Swimming increases endurance and strength and also stretches muscles, which is a big part of the Rx'd exercises.

FRankly I've never had any help with fibro from ibuprofen or any other OTC.

Grain -
You probably know more about Zanaflex than I do. All I know about Zanaflex is what I read on the more reliable websites. I was comparing muscle relaxants. I'm afraid to try it unless I have to go off tramadol.
Your Nucynta sounds promissing, but I agree you ought to be really careful about mixing it with anything. The thing that would keep me off it is the incidence of nausea and vomiting of 22%, since I've had stomach surgery for a large hiatal hernia and am afraid of reherniation.

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 9/26/2010 7:35 PM (GMT -6)   
I'm going to a PT for my therapy tomorrow. My insurance will only cover me for 40 visits a year with a $25 co-pay. I can get massages along with it if the doctor orders it, but it counts as a visit.
I heard that I need to keep up the exercises even after the therapy is done. That's way I was wondering about the Y.

Another side effect I've been suffering is profuse sweating! Phew! I feel like I'm melting away. I looked up the side effects for both drugs and both say they cause blurred vision and profuse sweating. It's 66 degrees here today and I'm soaking wet. I'm having to sit under a fan just to feel somewhat cooler.
Neither drug is good for my glaucoma. Both can increase my pressure in my eyes and send my blood sugar up.

I've got a mild ache right now that I'm praying will not increase when I go to work tomorrow. I'm going to live off of ibuprofen until she gets me a refill.
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