Hi ,When I post and you respond asking for my info, do I reply to my original post or start from new as I have here. I am new to this and am not sure how to do this posting/responding stuff. I have had AS since 2004 and have been on various biologics and had some success. However, on remicade I develope anit-bodies and had to go off. Then I went on Humira and plaquinil and had good releif until last Nov. I deveolped severe bulrred vision and tingling down my left side. As I am sure most of you know the new worry with biologics is deveolping MS or other nerve condition. The eye thing really scared me and took months to clear up. I briefly tried simponi and had shortness of breath. I moved from texas to New york two years ago and have trouble finding the right pain guy. I actually have an appointment in Jan with one I hear is very good. I am flying back to texas on Thursday to see my rhuematologist. I am currently on methrotexate and plaqunil. I stopped plaqunil for a couple months recently and the agony has come back! My vision was getting fuxzzy and I was worried about the possiblility of plaqunil effecting. I have an optic nuero appointment at the end of the month. I currently live in a small city and dr. availability is a problem. I am not handling this well as seem to get more depressed if I take oxycotin. Ironically , I have a 14 yr old pet pig with pretty severe arthritis His vet just came out and sedated him and injected his shoulder. She does a great job of manageing his pain. To bad she can't work on humans. For less severe pain I take norco 10/325 . I saw some wrote that they took nnuerontin, does it work for arthritis or just nueropathic pain?