Hello All...Finally Started Taking Cymbalta

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drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 11/6/2010 1:41 AM (GMT -6)   
Hey all, How is everyone feeling? I you have found some relief from your pain. The last time I posted, I said that my doctor wanted to start me on Cymbalta for my nerve pain, but first had to ween me off Prozac. I finally was able to start the Cymbalta about a week ago. My doctor started me at 60 MG once daily. Is this the standard dosage for Cymbalta, when prescribed for nerve pain? I'm going to be patient and give it a while to build up in my system, before deciding if it's helping. I'll try to post updates from time to time. I hope everyone is doing ok and that you're able to find some comfort. Take care...byeeeeeee

Eric
Herniated Lumbar Disks L5 S1, L2 L3
Herniated Cervical Disks C6 C7
Spinal Stenosis
Degenerative Arthritis Left Knee
Pes Planus Both Feet
Multiple Neuropathies
Brachial Plexus/Thoracic Outlet Syndrome
Nerve Pain in Arms, Hands, Back, Legs, Feet, Groin, Testicles

Retired Mom
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Date Joined Feb 2010
Total Posts : 1753
   Posted 11/6/2010 1:46 AM (GMT -6)   
Yeah Eric!

I hope this is your "med" of relief.
Retired Mom

straydog
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Date Joined Feb 2003
Total Posts : 16796
   Posted 11/6/2010 12:11 PM (GMT -6)   
Hi Eric, I looked at Drugs.com website about the Cymbalta because I could not remember what dosage I was on. From what I read there anything over 60mg a day showed no additional benefit so I am not sure. It said sometimes people will start 30mg the first week and then add another 30mg the 2nd week to help ward off any potential side effects. Keep in mind Cymbalta is an antidepressant and it is given in higher doses for depression and of course its used off label for neuropathic pain. I do know many people have success by adding Lyrica to the Cymbalta so that may be an option for you too. I would give it some time you really have not been on it what a full week. When do you see your dr again, soon?

I sure hope you get some relief one way or the other.
Moderator Chronic Pain Forum

drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 11/6/2010 3:54 PM (GMT -6)   
Straydog, it's my primary physician who put me on Cymbalta after I requested it. He started me at 60 MG, but I don't know if he plans on increasing it if the current level doesn't work. My pain doctor said the highest dose she's aware of is 90 MG, so she would probably increase it to 90 if I asked her to...I'll give 60 MG a chance first. I see the pain doc every month, next would be the end of november. I've had negative reaction to Lyrica when I tried it the first time, so I probably would avoid it. She mentioned Neurontin as well. Thanks retired mom & Paula for the kind thoughts. How are you guys feeling?
Herniated Lumbar Disks L5 S1, L2 L3
Herniated Cervical Disks C6 C7
Spinal Stenosis
Degenerative Arthritis Left Knee
Pes Planus Both Feet
Multiple Neuropathies
Brachial Plexus/Thoracic Outlet Syndrome
Nerve Pain in Arms, Hands, Back, Legs, Feet, Groin, Testicles

Jim1969
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Date Joined Jul 2009
Total Posts : 2042
   Posted 11/6/2010 4:16 PM (GMT -6)   
Typically Cymbalta is started at 30 mg and then increased every 1-3 weeks up to a max of 120 mg. There is some "disagreement" over the max dose among doctors. Some say max 90mg per day for nerve pain and others say max 120mg for nerve pain is acceptable since the makers of Cymbalta have set the max safe dose at that level for depression.

Cymbalta is what I call a cumulative medication in that the longer you take it the better it will work. I currently take 90 mg/day for my nueropathy and it works pretty well for me. I would estimate that I have a 95-98% reduction in the pain caused by the nueropathy in my feet and legs leaving for the most part only numbness.

straydog
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Date Joined Feb 2003
Total Posts : 16796
   Posted 11/6/2010 5:01 PM (GMT -6)   
Eric sorry to hear that you had trouble with Lyrica but perhaps Neurotin with it is something to consider if it comes down to it. Its like Jim says, its really all in the minds of the drs on what they will call their max dose of alot of meds. I do believe there is a cap of 120mg with it. You should give it time because it does have to build up like in your system. Thats tough especially if you feel it isn't working but if you give it the time needed you may be surprised. I do hope this works for you I do know you have suffered a lot with this mess, you are past due for a break. I would have my PM dr increase it if you feel it may need to be after some time. Keeping my fingers crossed for you.

Keep us posted on how you you are doing.
Moderator Chronic Pain Forum

skeye
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Date Joined Mar 2008
Total Posts : 3089
   Posted 11/6/2010 6:51 PM (GMT -6)   
Eric,

When I was taking Cymbalta (several years ago now), I started at 30 mg and then tapered up to 90 mg. Unfortunately, it did not help my pain, and actually made my depression much worse, so I had to stop it.

Be careful coming off of it (if you eventually do so). If you don't taper slowly enough you can get some really nasty side effects, like brain zaps, & believe me, they are not fun!

Best of luck with the Cymbalta! I hope it helps!

hugs,
Skeye
chronic retrobulbar eye pain, Asperger's syndrome, probable bipolar II, severe depression, & anxiety

recently implanted with a neurostimulator with leads on the supraobrital & infraorbital (ophthalmic) branches of the trigeminal nerve, resulting in a 50% decrease in pain (yippee!)

Mrs. Dani
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Date Joined Jun 2009
Total Posts : 2787
   Posted 11/6/2010 7:38 PM (GMT -6)   
 
   Dear Eric,
 
        That is good news! I do hope it helps once it has built up in your system. I have never taken it myself, but I have heard many good things about it re:pain. Let us know how it goes the more you become accustomed to it.  :-)
 
*hugg*
  dani

TWO roads diverged in a yellow wood
And sorry I could not travel both
And be one traveler, long I stood

Chronic Pain Moderator
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ReactiveConstellationNE
Regular Member


Date Joined Dec 2005
Total Posts : 256
   Posted 11/6/2010 10:25 PM (GMT -6)   
I have to be blunt and say that my own experiences with Cymbalta weren't just bad, they were horrifying....I had some truly bizarre and scary neurological side effects including "zombie" movements while asleep or in bed, where my arms would lift up towards vertical as if gravity had suddenly reversed and my arms were falling "up".....as well as severe jerking and sudden spasms of the limbs. It didn't have any positive effect on my pain.

Everyone is different of course, but my advice would be extreme vigilance in watching out for side effects.

Post Edited (exitwound) : 11/8/2010 4:21:04 PM (GMT-7)


MsBunky
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Date Joined Jan 2010
Total Posts : 1097
   Posted 11/7/2010 12:42 PM (GMT -6)   
Eric, I was started at 60mg one time per day and that lasted for about a month. I now take 60mg 2X per day - once in the morning and once at night.

I saw definite benefits at this level and have been able to maintain a steady 4/10 on the pain scale (as long as I take all my other meds as scheduled, and I am on other pain meds). My doctor and I have a great relationship and we talk through every change in my meds - why the change should happen, what I can expect, etc.

Every drug reacts differently for every person. When I first started on Cymbalta, I had three days of the most horrific nausea I've ever experienced (which is scary for me, as I am unable to physically vomit, due to a surgery for my GERD). I honestly thought I was going to die and for those three days, I did nothing but sit as motionless as possible on the couch. On day 4, I woke up and felt great. No nausea, no after affects, no major pain....it was pretty cool.

I hope you find relief with the Cymbalta. I tried Lyrica first and the side effects for me were terrible - weight gain like crazy, dizzy, vision problems, hallucinations...you name it. With Cymbalta, I've had nothing negative since those first three days, so it's been a God send for me.

Good luck!

hugs,
Pam
DX: Fibromyalgia, Severe Myofascial Pain, Chronic Pelvic Pain, Surgical Adhesions, IBS, IC-PBS, Carpal Tunnel (both wrists), FAI, Diabetes (just diagnosed), Reynauds, Opthalmic Migraines, Drug Related Hot Flashes, Hard Start for IV's, Unable to vomit due to surgery.

Meds: Oxycontin, Tramacet, Cymbalta, Cesamet, Flexeril, Clonidine + Vitamin D + Multi daily

antbuggey
Veteran Member


Date Joined May 2010
Total Posts : 594
   Posted 11/7/2010 4:57 PM (GMT -6)   
Hi Eric,

The first time I took Cymbalta, I had wonderful results! It seemed to work really well. I had to go off of it because of insurance changes. I went back on it recently and I don't feel like I am getting as much from it this time. However, I do have new stuff going on (probably RA....will find out Tuesday at my rheumy appt) that it may not help as much with. I guess I should not say it is not working as well this time because the nerve pain is better....it is the joint pain that is really bad now! Sorry, I am kind of talking in circles.....I do that a lot! lol!! Anyway, both times I started at 30mg and went to 60mg and stayed. My PCP did tell me that once we figure out the new problems, we may switch to 60mg twice a day! I, also, had a terrible time with Lyrica....dizzy, nauseous, off balance....yuck!

I hope you get good results with it!

Take care of you!
Beckey
Spinal Stenosis L3/L4, L4/L5 & L5/S1 with Nerve Impingement, Fibromyalgia, TMJ, GERD, Severe Depression, VERY Large Cyst Right Ovary causing mild twisting, Small Cysts Left Ovary & 3 Large Cysts Uterus and Possible RA

Medications - MS-Contin, Cymbalta, Famotidine and currently Prednisone

drjimmy
Regular Member


Date Joined Dec 2008
Total Posts : 110
   Posted 11/8/2010 5:36 PM (GMT -6)   
Beckey, that stinks that you're having so many problems and pain...I hope you find some relief with the possible increased dose...Pam, Thanks for the info...so far I'm lucky and have had no nausea, but also no pain relief at 60 MG once daily...I can't imagine going through what you did the first few days of Cymbalta...it's horrible, I'm sorry...Exitwound, that sounds nightmarish what you went through! Thanks for the heads up...I'll be aware...Dani, thanks for the warm wishes! I'll keep you posted...Skeye, I'm sorry that Cymbalta didn't help your pain and made your depression worse...that's a double whammy that no one deserves...If I stop taking it, I'll be sure to ween off it slowly, thanks...Straydog, thanks for the understanding and kind words...I'll give each dose enough time before increasin the dose and I'll try adding Neurontin if it doesn't help...I'll keep everyone posted on updates, thanks...Jim, I guess I got a head start at 60 MG once daily...I'm happy that most of your nerve pain is gone thanks to the cymbalta! Thanks for the info and advice...Again thanks everyone for taking the time to share your stories and advice and especially the warm wishes! It means and helps a lot! I hope you're all feeling less pain today and tomorrow.
Herniated Lumbar Disks L5 S1, L2 L3
Herniated Cervical Disks C6 C7
Spinal Stenosis
Degenerative Arthritis Left Knee
Pes Planus Both Feet
Multiple Neuropathies
Brachial Plexus/Thoracic Outlet Syndrome
Nerve Pain in Arms, Hands, Back, Legs, Feet, Groin, Testicles
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