ak angel read my mind. before i had read about you using Duragesic patches i thought about Suboxone at a pain control dose, (up to 32mg/24hrs.), or Subutex would be the same without the addition of naloxone that prevents IV abuse. the generic name is Buprenorphine which is a potent opioid, about 1omg of morphine sulfate IV equals 0.3mg Buprenex, it has a ceiling effect at 32mg/day but that would be equal to quite a lot of morphine. the great thing is it's effects on the breathing center of your brain are less depressant like and it has a ceiling of respritory depression unlike pure opioid-agonists. Buprenorphine is a opioid agonist/antagonists, it has a agonist effect on the mu-receptor and a antagonist effect at the kappa-opioid receptor and all kinds of weird unique effects at the other opioid receptors maybe giving it a advantage for certain types of pain like fibro.. it has very high binding affinity to all receptors so it will prevent or reverse other agonist opioids. i was on the max dose for pain; 2 tablets in the morning 1 afternoon and bedtime (8mg/2mg sublingual tabs.) and it did work well but it was so expensive it could not keep up. for your COPD Dx you may get better deals. Lunesta has respiratory depressant effects especially with an interaction with another depressant. i don't know your oxycodone dose or if it is conventional release but i would think the fentanyl patch is more of a risk, it never stops delivery of drug into your blood, even when your sleeping. Zanaflex may cause dizziness upon rising or drowsiness but it is not a central acting depressant that would potentate another. the drawback with Suboxone/Subutex or the newer patch(maybe not in US YET) is switching from the fentanyl patch that leaves drug concentrations in the fat that are not active until hours after the patch is removed. the period of hours/days may be longer until the first dose of buprenorphine is taken. the one other drawback is no breakthrough med would work other than more buprenorphine, with the new patch the sublingual tablets are used for breakthrough in Europe. also one study showed benzodiazepines like Valium or Klonopin had a deadly respiritory depressant effect interaction, both at perscribed amounts but it seems they have learned otherwise since then(2000-03) because they combine them now. it may be the best thing you ever did or the worst but it is worth a try and i would say to find a different sleep med because Lunesta is a dangerous med relatively. Seroquel at a low dose is gaining popularity for insomnia. it works for almost all but it cal effect lipids and glucose and strain the liver, but in a low dose most likely not. Melatonin is a great idea even if it does not work it is one of the most powerful anti-oxidants known. GABA, L-theanine, lemon balm, valerian, hops, kava, 5-HTP, and calcium/magnesium citrate or gluconate are some thing that can start to improve sleep. Tart cherry extact capsules contain high concentration of Melatonin and are more commonly used as a anti-inflammatory and joint health. GOD bless and best of luck to you.