Clinical trial of time-release hydrocodone

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Veteran Member

Date Joined Oct 2010
Total Posts : 932
   Posted 3/30/2011 3:18 PM (GMT -6)   
Howdie all,

I've posted a few times regarding my need to find a stronger time-release med than ultram. It just isn't managing my pain adequately any longer.

But, I'm worried about jumping up to a stronger option. So, I found a clinical trial for time-release hydrocodone. I contacted the researchers, went through an initial phone interview, and now have an appointment for a standard physical, blood panel, etc..

Next week I see my PM and will, of course, clear this with him. Since I find hydrocodone helpful but doesn't interfere with concentration as much as oxycodone, it seems like a suitable time-release option for me. However, it is a double-blind study and so I might get the placebo... but I'll take the chance. If I'm in more pain, I can just leave the study and move to what my PM recommends.

Has anyone here been part of a similar clinical trial? Any advice?

p.s. such a bad pain day today! I have so much work to do but the pain is too severe for me to concentrate. I'm glad to have this forum as an outlet and a means to distract myself on bad days.
C4-T4 Scoliosis (disk degeneration, stenosis, narrowed neuroforamen, bone spurs), RT hip and SI joint damage from car accident. Also, Supraventricular tacycardia and mitral valve prolapse syndrome.
Current meds: Ultram ER 300mg daily, breakthrough - hydrocodone 10-15mg, or oxycodone 5-7.5mg. .25-.5mg ativan as needed for sleep, Verapamil 240mg SR (for tachycardia).

Veteran Member

Date Joined Apr 2009
Total Posts : 856
   Posted 3/30/2011 5:23 PM (GMT -6)   
I've read about a trial for CR hydrocodone. I wonder if it's the same one. Have you tried any other long-acting medications, like morphine or Opana? If hydrocodone works well for you, then the CR will probably be great. I hope that you get into the trial, and don't get the placebo, because it seems like it would work well for you.

Veteran Member

Date Joined Apr 2010
Total Posts : 2265
   Posted 3/30/2011 10:01 PM (GMT -6)   
Good luck. I hope you get accepted into the clinical trial and that it all works out for you. I hope your pain is better than it was earlier. You take care. Good luck.

love and hugs
Dx: osteoarthritis, bursitis in left hip, Osteoarthrits in right hip, compression fracture in thoracic spine due to falling on frozen ground March 2001 , ddd, spinal stenosis, bone spurs, osteoarthritis in spine, osteoarthritis in both knees
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