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Regular Member

Date Joined Dec 2010
Total Posts : 80
   Posted 4/8/2011 2:48 PM (GMT -6)   
Finally changed my meds  I am now off of oxycontin and I am on Dilaudid and roxy.  He also gave me a script for long acting dilaudid.  is anyone taking this.  do you think they work?  The new formula of oxyontin doesn't work for me. 

Veteran Member

Date Joined Oct 2010
Total Posts : 924
   Posted 4/8/2011 4:25 PM (GMT -6)   
Dilaudid/Hydromorphone's bioavailability varies widely among individuals (10%-65%) and is metabolized somewhat differently than other opioids (partly via the UGT1A3 enzyme).

I tried Hydromorphone IR and it didn't have any effect on me... presumably I'm towards the lower range. I don't know if the ER mechanism alters the level of bioavailability, but I suspect that its benefits will also vary widely from individual to individual.

Like you, I'm starting a new long-acting agent this weekend: moving from Ultram ER 300mg to Kadian.

Hope it goes well for you.

BTW, if curious, I got the above data from:
C4-T4 Scoliosis (disk degeneration, stenosis, narrowed neuroforamen, bone spurs), RT hip and SI joint damage from car accident. Also, pectus excavatum, supraventricular tacycardia and mitral valve prolapse syndrome.
Current meds: Ultram ER 300mg daily, breakthrough - hydrocodone 10-15mg, or oxycodone 5-7.5mg. .25-.5mg ativan as needed for sleep, Verapamil 240mg SR (for tachycardia). [/gray

Veteran Member

Date Joined Aug 2006
Total Posts : 9661
   Posted 4/8/2011 9:48 PM (GMT -6)   
I couldn't tolerate the oxycontin either, but I'm not on the meds you are and will hope this
new combination helps with better control of your pain.
well wishes to you in hopes of a low pain day...
healing hugz
* So many dx's I could write a book* "It would be nice if we could use the edit button in real life"...

Forum Moderator

Date Joined Mar 2011
Total Posts : 1276
   Posted 4/9/2011 1:54 AM (GMT -6)   
Hi Jazzie - I've tried a long acting hydromorphone (called Jurnista) too and it wasn't good for me. I was on a 24-hour release but even on a comparative dose it did nothing much for my pain and what effects it did have, had worn off within about 8-10 hours. It also affected my eyesight.

Hoping that it works for you *hugs*

CRPS since 1999, diagnosed in 2005 and since spread to full body, spasms, dystonia & contractures, gastroparesis, orthostatic hypotension.

On Oxycontin/Endone, Topamax, Mobic, Magnesium, Florinef, Somac, Cipramil. Have a spinal cord stimulator, intrathecal pump with baclofen & bupivacaine and doing physio.

Regular Member

Date Joined Dec 2010
Total Posts : 80
   Posted 4/9/2011 3:19 PM (GMT -6)   
Thanks for  the feedback.  He gave me he long acting dilaudid which I will try on Monday.  I hope this works for me.  Right now my pain level is about an 7 and climbing.  Going to lie down.
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